Protein Info for CSW01_03510 in Vibrio cholerae E7946 ATCC 55056

Annotation: NADP(H)-dependent aldo-keto reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 352 PF00248: Aldo_ket_red" amino acids 23 to 343 (321 residues), 245.4 bits, see alignment E=3.3e-77

Best Hits

Swiss-Prot: 62% identical to TAS_ECOLI: Protein tas (tas) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to vcm:VCM66_0625)

Predicted SEED Role

"Putative oxidoreductase YeaE, aldo/keto reductase family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (352 amino acids)

>CSW01_03510 NADP(H)-dependent aldo-keto reductase (Vibrio cholerae E7946 ATCC 55056)
MALRQGSAMQYTKLPHSSLEISKICLGTMTFGEQNSQADAFQQLDYALERGVNFIDTAEM
YPVPPTAQTQGKTEEFIGNWLAKSGKREKIVLATKVAGPRNVPYIRDKMALDHRNIHQAV
DDSLRRLQTDYIDLYQLHWPQRQTNTFGQLNYPYPDKQEEVTLIETLEALNDLVRMGKVR
YIGVSNETPWGVMSYLRLAEKHELPRIVSIQNPYNLLNRSFEVGLAEISHLEGVKLLAYS
PLAFGALSGKYLNGARPAGARCTLHQRFSRYFTEQGILATEAYVALAQQFGLDPAQMALA
FVNQRPFVASNIIGATTMEQLKSNLDSLDISLNAELLQKIQEIGTTYSNPCP