Protein Info for CSW01_03430 in Vibrio cholerae E7946 ATCC 55056

Annotation: U32 family peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 292 transmembrane" amino acids 20 to 38 (19 residues), see Phobius details PF01136: Peptidase_U32" amino acids 91 to 237 (147 residues), 43.7 bits, see alignment E=1e-15

Best Hits

Swiss-Prot: 65% identical to YHBV_ECOLI: Uncharacterized protein YhbV (yhbV) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to vcm:VCM66_0609)

Predicted SEED Role

"FIG139928: Putative protease" in subsystem CBSS-214092.1.peg.3450

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (292 amino acids)

>CSW01_03430 U32 family peptidase (Vibrio cholerae E7946 ATCC 55056)
MKYALGPLLYFWPKQDVESFYTQAAASMADVIYLGETVCSKRREMKPQHWFEIAKSLSAA
GKQVVLSTMALLEAPSEINVMKKYIDNGDFAIEANDVSAIQMAHEKGLPFIVGPAVNTYN
AHTLKLFLKQGMIRWCMPVELSRDWLINTLQQCDELNIRGQFEVEVFSHGYLPLAYSARC
FTARAENRAKDECETCCIRYPTGIQVASQEGQSVFNLNGIQTQSGYCYNLVNDLPSMAGL
VDVVRLSPLGVETFQHLEQFKANEQGLKPQPITSHQCNGYWHQLAGLAVKNS