Protein Info for CSW01_03210 in Vibrio cholerae E7946 ATCC 55056

Annotation: iron ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 541 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 27 to 28 (2 residues), see Phobius details amino acids 49 to 76 (28 residues), see Phobius details amino acids 86 to 106 (21 residues), see Phobius details amino acids 137 to 157 (21 residues), see Phobius details amino acids 194 to 217 (24 residues), see Phobius details amino acids 237 to 254 (18 residues), see Phobius details amino acids 285 to 311 (27 residues), see Phobius details amino acids 328 to 351 (24 residues), see Phobius details amino acids 369 to 389 (21 residues), see Phobius details amino acids 408 to 430 (23 residues), see Phobius details amino acids 466 to 490 (25 residues), see Phobius details amino acids 514 to 533 (20 residues), see Phobius details PF00528: BPD_transp_1" amino acids 68 to 253 (186 residues), 51 bits, see alignment E=7.6e-18 amino acids 343 to 538 (196 residues), 37.3 bits, see alignment E=1.2e-13

Best Hits

KEGG orthology group: K02011, iron(III) transport system permease protein (inferred from 100% identity to vcj:VCD_003800)

Predicted SEED Role

"Ferric iron ABC transporter, permease protein" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (541 amino acids)

>CSW01_03210 iron ABC transporter permease (Vibrio cholerae E7946 ATCC 55056)
MKEKYFAWKASSLVLTTLLVLPILAIFYTAFGNSDEVFAHLLATVMPTYIFNTLVLTCSV
LLLALLFGVPSAWLIAMCKLPGERWLQWALVLPLAMPAYIIGYLFTHWFDYAGPIQIALR
DWTGWQAGSYWFPDIRSLGGASVVLALVLYPYVYLLCRAAFMEQNVTLLQSARLLKCSPW
QSFRRISLPLARPAIAVGLSLVAMETIGDFGTVSLFAVNTLTTAVYDTWLGYSNLNAAAK
ISAIMLVMVLLLLSSERYSRRRQKLYQTQFNSHEEYRYTLKGWRLWAALIWCWGLVAVAF
ILPLLQLISYAWTYFAQSWTTQFKEYAINSFTVSISAAVVAVLVALVANFYARLQNNRTS
VALMRLSSMGYAVPGTVLAIGILVPVLALDHLINDIAKMMEWGRPGLVFSGSLFAIVFAL
VVRFSAVAIGSIESSLSKVSPSLDMAARTMGCHANQMLKRVHLPLIRRGALIAGLLVFIE
SMKELNAAILLRPFNFETLATYVYNYASDERLELAALPAILLVLVGLIPLVMVNRSLEQK
H