Protein Info for CSW01_03160 in Vibrio cholerae E7946 ATCC 55056

Annotation: DNA/RNA nuclease SfsA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 256 TIGR00230: sugar fermentation stimulation protein" amino acids 13 to 241 (229 residues), 257.9 bits, see alignment E=3.8e-81 PF17746: SfsA_N" amino acids 25 to 92 (68 residues), 85.6 bits, see alignment E=2e-28 PF03749: SfsA" amino acids 96 to 239 (144 residues), 155.6 bits, see alignment E=7e-50

Best Hits

Swiss-Prot: 100% identical to SFSA_VIBCH: Sugar fermentation stimulation protein homolog (sfsA) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K06206, sugar fermentation stimulation protein A (inferred from 100% identity to vcm:VCM66_0555)

Predicted SEED Role

"Sugar/maltose fermentation stimulation protein homolog" in subsystem Fermentations: Mixed acid

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (256 amino acids)

>CSW01_03160 DNA/RNA nuclease SfsA (Vibrio cholerae E7946 ATCC 55056)
MPSPLAMNKKRNMHFSPPLQKGTLLKRYKRFLADVTLEDGSVITMHCANTGAMTGCAEPG
STVWFSTSDNPKRKYAHSWELTQTQAGHWICVNTARANALVVEAILAGEIPQLRGYDALS
TEVKYGHENSRIDILLKSDSQPHCFIEVKSVTLLDEIQGDKGQGYFPDAVTTRGQKHLRE
LAEVAKDGSRSILLFAVLHSGIEKVAPALHIDANYSQLLKAAQEAGVEVLCYKASLSKHE
IRMVSEVKFAHQVTKN