Protein Info for CSW01_03050 in Vibrio cholerae E7946 ATCC 55056

Annotation: cytochrome b

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 421 transmembrane" amino acids 33 to 56 (24 residues), see Phobius details amino acids 84 to 107 (24 residues), see Phobius details amino acids 117 to 139 (23 residues), see Phobius details amino acids 145 to 163 (19 residues), see Phobius details amino acids 184 to 206 (23 residues), see Phobius details amino acids 262 to 280 (19 residues), see Phobius details amino acids 304 to 317 (14 residues), see Phobius details amino acids 324 to 343 (20 residues), see Phobius details amino acids 358 to 379 (22 residues), see Phobius details amino acids 385 to 405 (21 residues), see Phobius details PF00033: Cytochrome_B" amino acids 23 to 211 (189 residues), 220.1 bits, see alignment E=3.6e-69 PF13631: Cytochrom_B_N_2" amino acids 93 to 281 (189 residues), 142.9 bits, see alignment E=1.5e-45 PF00032: Cytochrom_B_C" amino acids 295 to 396 (102 residues), 140.4 bits, see alignment E=3.3e-45

Best Hits

KEGG orthology group: K00412, ubiquinol-cytochrome c reductase cytochrome b subunit [EC: 1.10.2.2] (inferred from 100% identity to vch:VC0574)

Predicted SEED Role

"Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2)" in subsystem Ubiquinone Menaquinone-cytochrome c reductase complexes (EC 1.10.2.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.10.2.2

Use Curated BLAST to search for 1.10.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (421 amino acids)

>CSW01_03050 cytochrome b (Vibrio cholerae E7946 ATCC 55056)
MQALLDWVEKRLPAMNAYKKHLSEYPMPKNFNFWYLFGSLAMLVLVNQLLTGIWLTMNYV
PSGEGAFASIEYIMRDVEYGWLLRYMHSTGASAFFVVVYLHMFRGLIYGSYQKPRELLWI
FGMLIFLVLMAEAFMGYLLPWGQMSYWGAQVIISLFGAIPVIGDDLTLWIRGDYVISGAT
LNRFFALHVIALPIVLLLLIVLHILALHEVGSNNPDGIETKLPKGSMGEGYESQFKFHEY
YTKKYDIIDSIPFHPYGTVKDLIGVAGFLFLFCYVLFFNPEMGGYFLEPPNFEAANPLKT
PEHIAPVWYFTPFYAILRAVPDKLLGVIAMGASIVVLFLLPWLDRCKVRSYRYRSKFHLF
NIAQFTVSFIALGILGALPATPTYTLLAQIFSLCYFMFFVLLFFYSKNEATKPLPTRVTY
K