Protein Info for CSW01_03030 in Vibrio cholerae E7946 ATCC 55056

Annotation: cell division protein ZapE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 367 PF03969: AFG1_ATPase" amino acids 1 to 364 (364 residues), 600.8 bits, see alignment E=4.4e-185

Best Hits

Swiss-Prot: 57% identical to ZAPE_ECOLI: Cell division protein ZapE (zapE) from Escherichia coli (strain K12)

KEGG orthology group: K06916, (no description) (inferred from 100% identity to vco:VC0395_A0102)

Predicted SEED Role

"ATPase, AFG1 family" in subsystem Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (367 amino acids)

>CSW01_03030 cell division protein ZapE (Vibrio cholerae E7946 ATCC 55056)
MTPKQRYEKDLQRTDFYSDEAQARAVDALDNLYHQWLNYLNQPVVRPSVWQKLIGKKPTV
TQPPQGLYMWGGVGRGKTYLMDTFFEALPTEKKLRVHFHRFMYRVHDELRTLSDVSDPLE
IVADRFCAEANIICFDEFFVSDITDAMILGTLFEALFRRGIVLVATSNIAPKDLYRNGLQ
RARFLPAIALVETHCQILNVDSGVDYRLRTLQQAEIYHYPLDSKATDNLQRYFQQLISSE
QTPETQIDVNHRMITVEAAGDGVLYATFAQLCQTARSQNDYIELSKIYHTVLLADVKQMN
KSSDDAARRFIALVDEFYERHVKLIISAEVPLTDLYTDGLLEFEFKRCQSRLIEMQSHDY
LAKEHLG