Protein Info for CSW01_02950 in Vibrio cholerae E7946 ATCC 55056

Annotation: sodium ion-translocating decarboxylase subunit beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 376 transmembrane" amino acids 13 to 35 (23 residues), see Phobius details amino acids 42 to 61 (20 residues), see Phobius details amino acids 69 to 93 (25 residues), see Phobius details amino acids 105 to 127 (23 residues), see Phobius details amino acids 138 to 156 (19 residues), see Phobius details amino acids 163 to 182 (20 residues), see Phobius details amino acids 211 to 237 (27 residues), see Phobius details amino acids 258 to 275 (18 residues), see Phobius details amino acids 286 to 306 (21 residues), see Phobius details amino acids 317 to 336 (20 residues), see Phobius details amino acids 354 to 375 (22 residues), see Phobius details TIGR01109: sodium ion-translocating decarboxylase, beta subunit" amino acids 19 to 370 (352 residues), 565.9 bits, see alignment E=1.7e-174 PF03977: OAD_beta" amino acids 20 to 374 (355 residues), 529.2 bits, see alignment E=2.3e-163

Best Hits

KEGG orthology group: K01572, oxaloacetate decarboxylase, beta subunit [EC: 4.1.1.3] (inferred from 100% identity to vcj:VCD_001054)

Predicted SEED Role

"Oxaloacetate decarboxylase beta chain (EC 4.1.1.3)" in subsystem Na+ translocating decarboxylases and related biotin-dependent enzymes or Pyruvate metabolism I: anaplerotic reactions, PEP (EC 4.1.1.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.1.1.3

Use Curated BLAST to search for 4.1.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (376 amino acids)

>CSW01_02950 sodium ion-translocating decarboxylase subunit beta (Vibrio cholerae E7946 ATCC 55056)
MDGLITLWQETGIANFELGQIIMILVGCTLLFLAIRKGFEPLLLLPIGFGAVLANIPNAG
FTEPGGLLYYVYHIGIESGVFPLLIFMGVGAMTDFGALIANPKTLWLGAAAQLGIFATLF
GAILLNFVPGMEFSMADASSIAIIGGADGPTAIFLASQLSPDLLGAIAVAAYSYMALVPI
IQPPIMKALTTPEERKIKMAQLRHVGKTEKIVFPLVVLLMTILFLPAATPLVGMFCLGNL
MREAGVVDRLSKTAQNELINIVTIFLGLGVGSKLQAETFLNLETLGILALGAAAFSIGTA
GGVIMAKILNKFSKEDINPLIGAAGVSAVPMAARVVNKVGLEANPQNFLLMHAMGPNVAG
VLGSAVAAGVLLALVG