Protein Info for CSW01_02875 in Vibrio cholerae E7946 ATCC 55056

Annotation: DNA recombination/repair protein RecA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 354 TIGR02012: protein RecA" amino acids 4 to 324 (321 residues), 565.5 bits, see alignment E=1.8e-174 PF00154: RecA" amino acids 7 to 267 (261 residues), 478.1 bits, see alignment E=1.4e-147 PF08423: Rad51" amino acids 36 to 227 (192 residues), 36.6 bits, see alignment E=6.2e-13 PF06745: ATPase" amino acids 40 to 205 (166 residues), 30.7 bits, see alignment E=4.1e-11 PF21096: RecA_C" amino acids 271 to 326 (56 residues), 88.4 bits, see alignment E=5.5e-29

Best Hits

Swiss-Prot: 100% identical to RECA_VIBCH: Protein RecA (recA) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K03553, recombination protein RecA (inferred from 100% identity to vcj:VCD_001062)

MetaCyc: 84% identical to DNA recombination/repair protein RecA (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"RecA protein" in subsystem DNA-replication or DNA repair, bacterial or DNA repair, bacterial RecFOR pathway

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (354 amino acids)

>CSW01_02875 DNA recombination/repair protein RecA (Vibrio cholerae E7946 ATCC 55056)
MDENKQKALAAALGQIEKQFGKGSIMRLGDNRAMDVETISTGSLSLDIALGAGGLPMGRI
VEIFGPESSGKTTLTLELIAAAQREGKTCAFIDAEHALDPVYAKKLGVNIDELLVSQPDT
GEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEMGDSHMGLQARMLSQAMRKLTGN
LKQSNCMCIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAIKEGEEVVGNE
TRIKVVKNKIAAPFKEANTQIMYGQGFNREGELIDLGVKHKMVEKSGAWYSYNGDKIGQG
KANACKYLKENPEIAKTLDKKLREMLLNPENMQLIAETSSAADDVEFGAVPEEF