Protein Info for CSW01_02775 in Vibrio cholerae E7946 ATCC 55056

Annotation: glycerol-3-phosphate acyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase
  • amino acids 2 to 194 (193 residues), 248.1 bits, E=3.2e-78
• PF02660: G3P_acyltransf
  • amino acids 11 to 184 (174 residues), 182.6 bits, E=3.3e-58

Best Hits

Swiss-Prot: 100% identical to PLSY_VIBCH: Glycerol-3-phosphate acyltransferase (plsY) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K08591, glycerol-3-phosphate acyltransferase PlsY [EC: 2.3.1.15] (inferred from 100% identity to vco:VC0395_A0051)

Predicted SEED Role

"Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria

MetaCyc Pathways

• phosphatidylglycerol biosynthesis I (6/6 steps found)
• phosphatidylglycerol biosynthesis II (6/6 steps found)
• superpathway of phospholipid biosynthesis III (E. coli) (10/12 steps found)
• CDP-diacylglycerol biosynthesis I (4/4 steps found)
• CDP-diacylglycerol biosynthesis II (4/4 steps found)
• superpathway of cardiolipin biosynthesis (bacteria) (10/13 steps found)
• oleate biosynthesis III (cyanobacteria) (2/3 steps found)
• phosphatidate biosynthesis (yeast) (3/5 steps found)
• diacylglycerol and triacylglycerol biosynthesis (3/7 steps found)
• palmitoyl ethanolamide biosynthesis (2/6 steps found)
• superpathway of stearidonate biosynthesis (cyanobacteria) (2/6 steps found)
• stigma estolide biosynthesis (2/7 steps found)
• anandamide biosynthesis II (2/8 steps found)
• anandamide biosynthesis I (3/12 steps found)
• superpathway of phospholipid biosynthesis II (plants) (10/28 steps found)

KEGG Metabolic Maps

• Glycerolipid metabolism
• Glycerophospholipid metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.15

Use Curated BLAST to search for 2.3.1.15

Protein Sequence (208 amino acids)

>CSW01_02775 glycerol-3-phosphate acyltransferase (Vibrio cholerae E7946 ATCC 55056)
MTPLALSMIIFAYLLGSISSAVLICRVLRLPDPRNVGSQNPGATNVLRIGGKKAAVAVLL
CDMLKGTIPVWGGYFLNIEPFMLGLVAIAACLGHMYPIFFHFKGGKGVATALGAIAPIGL
DLTAMVMATWLVVVVLFRYSSLAALVTVLLAPLYTWLIKPQYTLPVAMLCCLIVLRHHQN
VKRLFAGTEPKVGEKNKKPSDDEESRVV