Protein Info for CSW01_02730 in Vibrio cholerae E7946 ATCC 55056

Annotation: diguanylate phosphodiesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 410 transmembrane" amino acids 260 to 276 (17 residues), see Phobius details amino acids 310 to 327 (18 residues), see Phobius details PF00563: EAL" amino acids 80 to 193 (114 residues), 36.9 bits, see alignment E=2.8e-13 PF08668: HDOD" amino acids 216 to 320 (105 residues), 28.9 bits, see alignment E=8.1e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to vcj:VCD_001090)

Predicted SEED Role

"Predicted signal transduction protein" in subsystem Flagellar motility

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (410 amino acids)

>CSW01_02730 diguanylate phosphodiesterase (Vibrio cholerae E7946 ATCC 55056)
MDSFIAKQAITDENLTIVGYELLFRNSEKNRYPEGVSESLATKKIIWQQFVDDTIDRVVE
SDKLCFINFPEDLLIDGYAEILPKDKVVIEVLENTIPTEKLLSVIRGLREKGYLFALDDV
TRTVFENWHDYLSLFDFVKIDTRRIDDDFLKLFFSLKPICCIALAEKVETNEQLESLKKN
GFLLFQGFYLDRPKVLRCATTEYANTESFELLIEVIKRDFNPSRLELILIRNPKLTVGLL
KYVNTIGKPLKPISSIQHAIVYLGLEQLRMFVFLLCSSTIHDKLDLDKYVYVLTRAKFCE
LMMGEIDHKLSSMAFISGMLSLSHLFLPNDNSELLSSLPISNDMRDAVLCRAGILGDVIS
ASEAYQNAKWCEALDFLNKYKIKIDGGLSKLYMDAIEWSSECRTLMKEVK