Protein Info for CSW01_02455 in Vibrio cholerae E7946 ATCC 55056
Annotation: YggS family pyridoxal phosphate enzyme
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to PLPHP_VIBCH: Pyridoxal phosphate homeostasis protein (VC_0461) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
KEGG orthology group: K06997, (no description) (inferred from 99% identity to vcm:VCM66_0446)Predicted SEED Role
"Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (236 amino acids)
>CSW01_02455 YggS family pyridoxal phosphate enzyme (Vibrio cholerae E7946 ATCC 55056) MRSIQQNIEHITAQIESAQQKCGRARSSVQLLAVSKTKPVEAILEATQAGQRYFGENYVQ EGVDKIRYFAEHHPQLALEWHFIGPLQSNKTRLVAEHFDWVHTIDREKIALRLSEQRPVN MPPLQVLIQVNTSGEASKSGIEPQQLFTLAELISRLPNLTLRGLMSIPENVPDYPAQLAA FTQLAELQQQLAQKYPQIDTLSMGMSGDMQAAIEAGSTIVRIGTAIFGERDYSRNA