Protein Info for CSW01_02250 in Vibrio cholerae E7946 ATCC 55056

Annotation: DUF3394 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 854 transmembrane" amino acids 32 to 53 (22 residues), see Phobius details amino acids 67 to 84 (18 residues), see Phobius details amino acids 96 to 115 (20 residues), see Phobius details amino acids 123 to 140 (18 residues), see Phobius details amino acids 150 to 168 (19 residues), see Phobius details amino acids 192 to 213 (22 residues), see Phobius details amino acids 242 to 268 (27 residues), see Phobius details amino acids 298 to 316 (19 residues), see Phobius details amino acids 321 to 341 (21 residues), see Phobius details amino acids 361 to 382 (22 residues), see Phobius details amino acids 389 to 410 (22 residues), see Phobius details amino acids 439 to 458 (20 residues), see Phobius details amino acids 464 to 482 (19 residues), see Phobius details amino acids 514 to 539 (26 residues), see Phobius details amino acids 546 to 569 (24 residues), see Phobius details amino acids 575 to 630 (56 residues), see Phobius details amino acids 642 to 663 (22 residues), see Phobius details amino acids 669 to 688 (20 residues), see Phobius details amino acids 700 to 720 (21 residues), see Phobius details amino acids 830 to 846 (17 residues), see Phobius details TIGR02123: TRAP transporter, 4TM/12TM fusion protein" amino acids 33 to 728 (696 residues), 701.6 bits, see alignment E=5.4e-215 PF06808: DctM" amino acids 134 to 402 (269 residues), 169 bits, see alignment E=1.6e-53 amino acids 418 to 666 (249 residues), 96.4 bits, see alignment E=1.8e-31 PF11874: DUF3394" amino acids 673 to 852 (180 residues), 239.2 bits, see alignment E=2.5e-75

Best Hits

KEGG orthology group: None (inferred from 100% identity to vch:VC0429)

Predicted SEED Role

"TRAP-type uncharacterized transport system, fused permease component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (854 amino acids)

>CSW01_02250 DUF3394 domain-containing protein (Vibrio cholerae E7946 ATCC 55056)
MTQTTTPSQDVQEMVAQADTGARAPKGLPGRVLWFVPLCWSLFQLWYASPLPFIFDFGVL
NDTQARSIHLTFAVFLAFTAYPAMKGSPRDRIPLTDWLLALAGSFSAAYIYLFYAELAGR
SGAPTQFDVIASVVGMVLLLEATRRALGPPLMMVAALFLLYTFAGPYMPDVIAHKGASLN
KAMSHLWLTTEGVFGVALGVSTSFVFLFVLFGAMLERAGAGAYFIKVAFSMLGHMRGGPA
KAAVVASGLSGLVSGSSIANVVTTGTFTIPLMKRVGFPGTKAGAVEVAASTNGQLTPPIM
GAAAFLMVEYVGISYVEVIKAAILPALISYIALIYIVHLEACKAGMSGLPRRHQSTVAQK
LLSFTATILGLCVISAVVYYGIGWTKEAFGDAATPILTVVLLAAYVGLVKISAPYAKEGL
GIDENLQYVPDVAPTLKSGLHYLLPIVVLVWCLTVERFSPGLSAFWASVFMIFILLTQRP
LMALFNRTGSLGDAAKEGVTDLLESLVSGARNMIGIGVATAAAGTVVGVVTLTGIGLVMT
DFVEFISGGNLMLMLIFTAVISLILGMGLPTTANYIVVSTLMAPVIVTLGAEHGLIIPLI
AVHLFVFYFGILADDTPPVGLAAFAAAAIAKSDPIRTGIQGFAYDIRTAILPFMFVFNTQ
LLLMGIDSWWHLMLTILSSITAMLLFSAATQGWWLTKTKWWEVVALLVLTFTFFRPGFWW
DMVYPAQVMYAGTKLEQIVEQAPVGQPIQMIVAGENLKGEYTSKTVQLPFEDRAVSAQER
IASMGLTLLNDKNRMLVEMVEFGSPAEAAGIDFDWEIRSVVVDSDRPMKEWVFLPAILLT
LLLAWNQKRRIKKA