Protein Info for CSW01_02185 in Vibrio cholerae E7946 ATCC 55056

Annotation: rod shape-determining protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 347 TIGR00904: cell shape determining protein, MreB/Mrl family" amino acids 9 to 339 (331 residues), 544 bits, see alignment E=6.1e-168 PF06723: MreB_Mbl" amino acids 11 to 338 (328 residues), 492 bits, see alignment E=1.6e-151 PF00022: Actin" amino acids 36 to 205 (170 residues), 31.7 bits, see alignment E=1.6e-11 PF00012: HSP70" amino acids 99 to 207 (109 residues), 50.2 bits, see alignment E=3.2e-17 PF14450: FtsA" amino acids 162 to 319 (158 residues), 46.5 bits, see alignment E=1.2e-15

Best Hits

Swiss-Prot: 90% identical to MREB_SHIFL: Cell shape-determining protein MreB (mreB) from Shigella flexneri

KEGG orthology group: K03569, rod shape-determining protein MreB and related proteins (inferred from 100% identity to vco:VC0395_A2834)

Predicted SEED Role

"Rod shape-determining protein MreB" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (347 amino acids)

>CSW01_02185 rod shape-determining protein (Vibrio cholerae E7946 ATCC 55056)
MFKKLRGMFSNDLSIDLGTANTLIYVKGQGIVLDEPSVVAIRQDKGRGGKTVAAVGHAAK
QMLGRTPGNISAIRPMKDGVIADFYVTEKMLQHFIRQVHDNSVLKPSPRVLVCVPCGSTQ
VERRAIRESALGAGAREVYLIDEPMAAAIGAGLRVSEPTGSMVIDIGGGTTEVAVISLNG
VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAEKIKHEIGSAYPGDDVQEIEVRGRN
LAEGVPRSFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISENGMVLTGGGALL
KDLDRLLMEETGIPVVIADDPLTCVARGGGKALEMIDMHGGDLFSEE