Protein Info for CSW01_02150 in Vibrio cholerae E7946 ATCC 55056

Annotation: MSHA biogenesis protein MshB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 184 transmembrane" amino acids 7 to 29 (23 residues), see Phobius details PF07963: N_methyl" amino acids 3 to 28 (26 residues), 30.2 bits, see alignment 1.2e-11 TIGR02532: prepilin-type N-terminal cleavage/methylation domain" amino acids 5 to 28 (24 residues), 27.2 bits, see alignment (E = 1.2e-10)

Best Hits

KEGG orthology group: K10925, MSHA pilin protein MshB (inferred from 100% identity to vcm:VCM66_0393)

Predicted SEED Role

"MSHA pilin protein MshB" in subsystem Mannose-sensitive hemagglutinin type 4 pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (184 amino acids)

>CSW01_02150 MSHA biogenesis protein MshB (Vibrio cholerae E7946 ATCC 55056)
MKKMQQGFSLVELVIVIVVVGLLAVAALPRFLDVTDEAKKASIEGVAGGFATGVLSARAQ
WEAQARPTLTANNYPSINYDGVNFWLTTSATSGYRDGYPLGLNTDDATYPSGLTDQACID
LMNNLLQNPPQVGTETQAASNSNYKYSAKANSGAATCTYAQNEKGSQHEFVYEVNTGRVT
VTLQ