Protein Info for CSW01_01855 in Vibrio cholerae E7946 ATCC 55056

Annotation: DUF2065 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 68 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details amino acids 49 to 67 (19 residues), see Phobius details PF09838: DUF2065" amino acids 11 to 65 (55 residues), 78.5 bits, see alignment E=1.6e-26

Best Hits

Swiss-Prot: 50% identical to YJET_ECOLI: Uncharacterized protein YjeT (yjeT) from Escherichia coli (strain K12)

KEGG orthology group: K09937, hypothetical protein (inferred from 100% identity to vcj:VCD_001272)

Predicted SEED Role

"Putative inner membrane protein YjeT (clustered with HflC)" in subsystem Hfl operon

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (68 amino acids)

>CSW01_01855 DUF2065 domain-containing protein (Vibrio cholerae E7946 ATCC 55056)
MLFGVNMSQTLWVALGLVLIVEGLGPLFAPRGWRQMVAQLSLQPDNQLRRIGGCLVVAGA
VIAYVFAR