Protein Info for CSW01_01540 in Vibrio cholerae E7946 ATCC 55056

Annotation: 3-phenylpropionate MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 396 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 42 to 61 (20 residues), see Phobius details amino acids 73 to 90 (18 residues), see Phobius details amino acids 96 to 115 (20 residues), see Phobius details amino acids 136 to 154 (19 residues), see Phobius details amino acids 160 to 177 (18 residues), see Phobius details amino acids 205 to 225 (21 residues), see Phobius details amino acids 240 to 259 (20 residues), see Phobius details amino acids 266 to 285 (20 residues), see Phobius details amino acids 291 to 314 (24 residues), see Phobius details amino acids 326 to 349 (24 residues), see Phobius details amino acids 355 to 373 (19 residues), see Phobius details PF12832: MFS_1_like" amino acids 13 to 362 (350 residues), 176.7 bits, see alignment E=8e-56 PF07690: MFS_1" amino acids 16 to 334 (319 residues), 45.1 bits, see alignment E=6.6e-16

Best Hits

KEGG orthology group: K05820, MFS transporter, PPP family, 3-phenylpropionic acid transporter (inferred from 100% identity to vco:VC0395_A2694)

Predicted SEED Role

"Probable 3-phenylpropionic acid transporter" in subsystem Cinnamic Acid Degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (396 amino acids)

>CSW01_01540 3-phenylpropionate MFS transporter (Vibrio cholerae E7946 ATCC 55056)
MFTPTPYGWISQYFIGFFFAYGVYLPFWSLWFEDQGVSATDIGVLVGIGFATRCVANLVL
TPRLHRVEQLMPALRWLSFAAMLFVGFHFFTGGSFWLMALATVLFNLCCGPVVPISDAMA
NYYAKLKMLDYGRTRLWGSIAFIAGSTVVGFLVAKWGSLMILYTALVGVAVSWLLSLRQI
TPMPVTEHEAHAVRPKLKELLTEWPVVKFLLLVALIQGSHAAYYSFGSIYWKQAGHSEDI
IGYLWSLGVVAEVLVFAFSKRWFAGWSLRTLFFVASLGVIARWGLTASTTTILALVAIQL
LHGVTFAIAHIAAIQYIQHAPQNKMVALQALYNAIPLGAVIAAVTTLSGWGYEHWGAAVF
WAMAAMGGLALLIRVDTPPSTVQDGNALKAEPEAQN