Protein Info for CSW01_01470 in Vibrio cholerae E7946 ATCC 55056

Annotation: permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 458 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details amino acids 35 to 53 (19 residues), see Phobius details amino acids 64 to 86 (23 residues), see Phobius details amino acids 110 to 138 (29 residues), see Phobius details amino acids 148 to 165 (18 residues), see Phobius details amino acids 180 to 207 (28 residues), see Phobius details amino acids 238 to 262 (25 residues), see Phobius details amino acids 279 to 299 (21 residues), see Phobius details amino acids 311 to 332 (22 residues), see Phobius details amino acids 340 to 363 (24 residues), see Phobius details amino acids 370 to 391 (22 residues), see Phobius details amino acids 397 to 421 (25 residues), see Phobius details amino acids 434 to 457 (24 residues), see Phobius details PF02447: GntP_permease" amino acids 13 to 456 (444 residues), 393.2 bits, see alignment E=1.5e-121 TIGR00791: transporter, gluconate:H+ symporter (GntP) family" amino acids 14 to 457 (444 residues), 351.2 bits, see alignment E=4.8e-109 PF03600: CitMHS" amino acids 29 to 387 (359 residues), 45.9 bits, see alignment E=4.5e-16

Best Hits

KEGG orthology group: K03299, gluconate:H+ symporter, GntP family (inferred from 100% identity to vco:VC0395_A2664)

Predicted SEED Role

"Low-affinity gluconate/H+ symporter GntU" in subsystem D-gluconate and ketogluconates metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (458 amino acids)

>CSW01_01470 permease (Vibrio cholerae E7946 ATCC 55056)
MDPLLQTSDPTYLLTVAAVAIIALLLLIIRFKIHAFASLTLVSLGTAIATGVASDKVVST
MMTGFGGTLASVALLVGLGAMIGKILEVTGGAKVLADTLIGRFGEQRAPFALGVASLLFG
FPIFFDAGLIVMMPIIFSVAKRFGGSPLKYALPSAGAFAVMHAFVPPHPGPVAAAELLGA
NIGLLLIVGLLVAIPTWYLGAYLFGLYAGKKFDIPLSKAFFNTDAIIDEAKLPKFATVMT
ILVLPVLLIFMDTGLNTLAVAGMIDGKAPAVEFLRMLGKTPIALLITLLVCIAAFAKDYG
MARLEKLCGDSLAPICAVILVTGAGGMFGGVLRASGIGSALAGVLSDTGMPVVVAAFVIA
TCLRVAQGSATVALTTTAALIAPTVAATTGLSDLDLCFIVISIAGGATVLSHFNDSGFWL
VSRLMEMDEKTTLKTWTVMETLLGGIAFLIVATLSFIL