Protein Info for CSW01_01310 in Vibrio cholerae E7946 ATCC 55056

Annotation: long-chain fatty acid--CoA ligase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 471 transmembrane" amino acids 186 to 202 (17 residues), see Phobius details amino acids 214 to 232 (19 residues), see Phobius details PF00501: AMP-binding" amino acids 10 to 336 (327 residues), 176.7 bits, see alignment E=6.8e-56 PF13193: AMP-binding_C" amino acids 385 to 462 (78 residues), 52.1 bits, see alignment E=1.1e-17

Best Hits

KEGG orthology group: None (inferred from 100% identity to vch:VC0249)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (471 amino acids)

>CSW01_01310 long-chain fatty acid--CoA ligase (Vibrio cholerae E7946 ATCC 55056)
MSVVERIFNHSESRPDCIAVYENDRTISYENLASDIKKTAAKLVSLGVTSEDAVLVRSNN
SYSFILLYFSIHYVGAKFVNVAPDSDVSYVSFIEDKVNPKLFIEKSQDFIRNIDSYTFDN
IFPPQARGIADIMFTSGTTGEPKGVLLSHKSLVLATEHIISHVKNTNEDVELLLMPLSHS
FAMARMRTSLFAGGAIVVGCSFKQLKSVFKAIEFYKVTGLGLVPSAWSYITLMTKDLIRK
YSEQLNFIEFGSAHFPFEDKKQVAEWFPNTNVVMHYGLTEVSRATFIDFHNDDINAVGHR
YRGADFKIIDNKGAEVIEGEEGEIVFKAPWMLDGYFENSQLTSDCFVEGYFKTGDLGRVV
GDYLFLTGRLKEIINVGGKKVSPDQVEKVLSEALGVQECACAALSDANMGEVVQAYIVVK
SGWDCENVISNIKETINGQLPMHMRPKKYSIVSALPKTVSGKVQRYKLSSE