Protein Info for CSW01_01135 in Vibrio cholerae E7946 ATCC 55056

Annotation: nucleoid occlusion factor SlmA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 196 PF00440: TetR_N" amino acids 18 to 58 (41 residues), 40.2 bits, see alignment 2.4e-14 PF22276: SlmA-like_C" amino acids 80 to 196 (117 residues), 177.8 bits, see alignment E=7e-57

Best Hits

Swiss-Prot: 100% identical to SLMA_VIBCH: Nucleoid occlusion factor SlmA (slmA) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K05501, TetR/AcrR family transcriptional regulator (inferred from 100% identity to vcm:VCM66_0202)

Predicted SEED Role

"Transcriptional regulator SlmA, TetR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (196 amino acids)

>CSW01_01135 nucleoid occlusion factor SlmA (Vibrio cholerae E7946 ATCC 55056)
MAGNKKINRREEILQALAEMLESNEGASRITTAKLAKQVGVSEAALYRHFPSKARMFEGL
IEFIEESLMSRINRIFDEEKDTLNRIRLVMQLLLAFAERNPGLTRILSGHALMFENERLR
DRINQLFERIETSLRQILRERKLREGKSFPVDENILAAQLLGQVEGSLNRFVRSDFKYLP
TANFDEYWALLSAQIK