Protein Info for CSW01_01085 in Vibrio cholerae E7946 ATCC 55056

Annotation: MurR/RpiR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 282 PF01418: HTH_6" amino acids 1 to 75 (75 residues), 75.9 bits, see alignment E=3e-25 PF01380: SIS" amino acids 129 to 256 (128 residues), 64.9 bits, see alignment E=1e-21 PF13580: SIS_2" amino acids 170 to 213 (44 residues), 33.1 bits, see alignment 7.8e-12

Best Hits

Swiss-Prot: 41% identical to MURR_ECOLI: HTH-type transcriptional regulator MurR (murR) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to vco:VC0395_A2584)

Predicted SEED Role

"Sialic acid utilization regulator, RpiR family" in subsystem Sialic Acid Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (282 amino acids)

>CSW01_01085 MurR/RpiR family transcriptional regulator (Vibrio cholerae E7946 ATCC 55056)
MSVLQRIVSRRTQLSESGRQIGDWVLANAAQAAAMTSQDLAAWANVSQSSIVKFTQRLGF
KGYSEFKLALTEELGRKQVMVNQPLHSNILADDPVAVIAQKLVQTKTEAMFHTTNALRLD
EFSEAISWIQQAVRVQIIGIGGSALVAKDLAFKLLKLGITALTEQDSHVQIATARTLHSQ
DVLIAISFSGEKREILIAAEAAKQQGAKVIALTTPNKNRLREIADLALDTIADETQHRSS
AIASRTAQNVLTDLIFLTLTQQRETSARQLIDDISSDIRQMR