Protein Info for CSW01_01060 in Vibrio cholerae E7946 ATCC 55056

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 611 transmembrane" amino acids 41 to 62 (22 residues), see Phobius details amino acids 85 to 107 (23 residues), see Phobius details amino acids 158 to 179 (22 residues), see Phobius details amino acids 185 to 205 (21 residues), see Phobius details amino acids 269 to 287 (19 residues), see Phobius details amino acids 293 to 312 (20 residues), see Phobius details PF00664: ABC_membrane" amino acids 42 to 311 (270 residues), 62.2 bits, see alignment E=6.6e-21 PF00005: ABC_tran" amino acids 380 to 533 (154 residues), 121.7 bits, see alignment E=3.6e-39

Best Hits

Swiss-Prot: 58% identical to Y1051_HAEIN: Uncharacterized ABC transporter ATP-binding protein HI_1051 (HI_1051) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K06147, ATP-binding cassette, subfamily B, bacterial (inferred from 100% identity to vcj:VCD_001416)

Predicted SEED Role

"Lipid A export ATP-binding/permease protein MsbA" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (611 amino acids)

>CSW01_01060 ABC transporter ATP-binding protein (Vibrio cholerae E7946 ATCC 55056)
MFMFQWFEKLTEPFPAQEPQTPPKSLVAFCRYYTQGFEKPLLLMSLLSACVAMAEVTLVR
YMGEIVDILSTQERHQFWEMHGERLWTMAALVLVVMPILALVHSMLLHQTILGNYPMSIR
WSTHRYLLKQSIGFFQRDFAGRVATKVMQNANSVRETVLKLVDLSVYIAVYMVSMLVMIA
EADKILVVPILVWLLFYIAIQVYFVPRLKTISTDQANAQSQMTGRIVDTYTNITTVKLFS
HSQRETTYAKSGMKQFLHTVYRQMRTLTSLLYSVDLINYLLLFSIAALSIQLWLAETVTV
GVIAIGITIALRMQGMSKWIMWEIRALFESVGTVIDSMNTIANPVEIEDRPQAKSLQVKF
GELSFSQVRFGYSAQKTVFDDLNLVIQAGEKVGIVGRSGAGKSTLVNLLLRFYDVQSGQI
RIDGQDISHVSQESLRRHIGMITQDTSLLHRSIRDNILYGNPDADQAAIEEAARQAHAHD
FIQELQDEQGRTGYDVQVGERGVKLSGGQRQRIAIARVLLKNAPILIMDEATSALDSEVE
SAIQENLHTLMAGKTVIAIAHRLSTIAAMDRLIVMDEGKIVEQGTHQELLAHKGIYAQLW
AHQTGGFIGEA