Protein Info for CSW01_00965 in Vibrio cholerae E7946 ATCC 55056

Annotation: cyclic AMP-GMP synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 436 PF21654: DncV-like_NTFase" amino acids 107 to 197 (91 residues), 99.1 bits, see alignment E=2.3e-32 PF21713: DncV_C" amino acids 276 to 409 (134 residues), 219.7 bits, see alignment E=1.1e-69

Best Hits

Swiss-Prot: 100% identical to DNCV_VIBCH: Cyclic GMP-AMP synthase (dncV) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: None (inferred from 100% identity to vcj:VCD_000626)

MetaCyc: 100% identical to cyclic AMP-GMP synthase (Vibrio cholerae O1 biovar El Tor str. N16961)
2.7.7.-

Predicted SEED Role

"FIG01202724: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (436 amino acids)

>CSW01_00965 cyclic AMP-GMP synthase (Vibrio cholerae E7946 ATCC 55056)
MRMTWNFHQYYTNRNDGLMGKLVLTDEEKNNLKALRKIIRLRTRDVFEEAKGIAKAVKKS
ALTFEIIQEKVSTTQIKHLSDSEQREVAKLIYEMDDDARDEFLGLTPRFWTQGSFQYDTL
NRPFQPGQEMDIDDGTYMPMPIFESEPKIGHSLLILLVDASLKSLVAENHGWKFEAKQTC
GRIKIEAEKTHIDVPMYAIPKDEFQKKQIALEANRSFVKGAIFESYVADSITDDSETYEL
DSENVNLALREGDRKWINSDPKIVEDWFNDSCIRIGKHLRKVCRFMKAWRDAQWDVGGPS
SISLMAATVNILDSVAHDASDLGETMKIIAKHLPSEFARGVESPDSTDEKPLFPPSYKHG
PREMDIMSKLERLPEILSSAESADSKSEALKKINMAFGNRVTNSELIVLAKALPAFAQEP
SSASKPEKISSTMVSG