Protein Info for CSW01_00745 in Vibrio cholerae E7946 ATCC 55056

Annotation: signal recognition particle-docking protein FtsY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 391 PF02881: SRP54_N" amino acids 106 to 168 (63 residues), 56.9 bits, see alignment E=3.9e-19 TIGR00064: signal recognition particle-docking protein FtsY" amino acids 115 to 387 (273 residues), 383.4 bits, see alignment E=2.9e-119 PF06414: Zeta_toxin" amino acids 183 to 293 (111 residues), 31.3 bits, see alignment E=2.8e-11 PF00448: SRP54" amino acids 187 to 387 (201 residues), 260.5 bits, see alignment E=1.8e-81

Best Hits

Swiss-Prot: 52% identical to FTSY_BUCAI: Signal recognition particle receptor FtsY (ftsY) from Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)

KEGG orthology group: K03110, fused signal recognition particle receptor (inferred from 100% identity to vch:VC0147)

Predicted SEED Role

"Signal recognition particle receptor protein FtsY (=alpha subunit) (TC 3.A.5.1.1)" in subsystem Bacterial Cell Division or Two cell division clusters relating to chromosome partitioning or Universal GTPases (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (391 amino acids)

>CSW01_00745 signal recognition particle-docking protein FtsY (Vibrio cholerae E7946 ATCC 55056)
MTEKKKRGLLSWLGFGDEEKSQTTATDTQTQDEPQSQADVEAVAIQTETALTETETETET
ETETETETETATVEPARIVEQEKPTESFFARLKRSLSRTKANIGAGFFGLFKGKKIDDDL
FEELEEQLLIADVGMDTTSKIIANLTARASRQQLRDGEALYGLLKEEMAEILSQVEQPLV
IDTEKKPYVILMVGVNGVGKTTTIGKLAKQFQAQGKKVMLAAGDTFRAAAVEQLQVWGER
NQVPVIAQHTGADSASVIYDAIEAAKARGIDVVIADTAGRLQNKSNLMEELRKIVRVMKK
IDDSAPHEIMLTLDAGTGQNAISQAKLFSDVAPITGITLTKLDGTAKGGVIFAIADQFQI
PIRYIGVGEKIDDLRPFATQEFIDALFSREE