Protein Info for CSW01_00565 in Vibrio cholerae E7946 ATCC 55056

Annotation: GTP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 220 TIGR03598: ribosome biogenesis GTP-binding protein YsxC" amino acids 11 to 194 (184 residues), 238.2 bits, see alignment E=2.7e-75 PF02421: FeoB_N" amino acids 29 to 164 (136 residues), 29.2 bits, see alignment E=9.5e-11 PF01926: MMR_HSR1" amino acids 29 to 147 (119 residues), 64.7 bits, see alignment E=1.2e-21

Best Hits

Swiss-Prot: 100% identical to ENGB_VIBCH: Probable GTP-binding protein EngB (engB) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K03978, GTP-binding protein (inferred from 100% identity to vco:VC0395_A2407)

Predicted SEED Role

"GTP-binding protein EngB" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (220 amino acids)

>CSW01_00565 GTP-binding protein (Vibrio cholerae E7946 ATCC 55056)
MSVKIHYQNTHFITSAPDIRHLPEDEGIEIAFAGRSNAGKSSSLNRLTNQKNLAKTSKTP
GRTQLINLFKVADGCHIVDLPGYGFAQVPLEMKLKWQRALGEYLQKRQSLKGLVVLMDIR
HPMKDLDQQLIIWAVECGIPVQVMLTKADKLKSGARKAQVLKVREEAKTFGGDVAVDAFS
SLSGIGVDTLRAKLDEWYAPMLAALAEQEEGEQPESSTDQ