Protein Info for CSW01_00545 in Vibrio cholerae E7946 ATCC 55056

Annotation: TatD family deoxyribonuclease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 255 TIGR00010: hydrolase, TatD family" amino acids 1 to 252 (252 residues), 231 bits, see alignment E=7.7e-73 PF01026: TatD_DNase" amino acids 2 to 252 (251 residues), 252.7 bits, see alignment E=1.9e-79

Best Hits

KEGG orthology group: K03424, TatD DNase family protein [EC: 3.1.21.-] (inferred from 100% identity to vcm:VCM66_0103)

Predicted SEED Role

"Putative deoxyribonuclease similar to YcfH, type 2" in subsystem YcfH

Isozymes

Compare fitness of predicted isozymes for: 3.1.21.-

Use Curated BLAST to search for 3.1.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (255 amino acids)

>CSW01_00545 TatD family deoxyribonuclease (Vibrio cholerae E7946 ATCC 55056)
MIDTHAHVYASEFDHDRDEVIARARQVGIEKILMPNIDLNSIAPMLATEKAYPDLCHSMM
GLHPCYVDANVKQTLATIYEWFSRHTFIAVGEIGIDLYWDKTFKAEQEMAFLTQLNWAKE
LDLPVVIHTRDSLNETLALLKQAQDGRLRGVFHCFGGSVDEAKAINDLGFHLGIGGVSTF
KNSGMDQVIPQLDLNYVILETDCPYLAPVPHRGKRNEPMLTHLISEKVAQLRSLPLGEVI
KITNNNSKALFGLDK