Protein Info for CSW01_00465 in Vibrio cholerae E7946 ATCC 55056

Annotation: twin-arginine translocase subunit TatB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 133 signal peptide" amino acids 1 to 39 (39 residues), see Phobius details TIGR01410: twin arginine-targeting protein translocase TatB" amino acids 2 to 81 (80 residues), 117 bits, see alignment E=2.1e-38 PF02416: TatA_B_E" amino acids 4 to 34 (31 residues), 27.5 bits, see alignment 7.4e-11

Best Hits

Swiss-Prot: 100% identical to TATB_VIBCH: Sec-independent protein translocase protein TatB (tatB) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K03117, sec-independent protein translocase protein TatB (inferred from 100% identity to vcm:VCM66_0087)

Predicted SEED Role

"Twin-arginine translocation protein TatB" in subsystem Twin-arginine translocation system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (133 amino acids)

>CSW01_00465 twin-arginine translocase subunit TatB (Vibrio cholerae E7946 ATCC 55056)
MFDIGFWELVLIAIVALVVLGPERLPHAIRSVAKFVSAAKSMANSVKDELAHELKVQELQ
ENLRKAEQMGMQNLSPELQKSVESLKQAAQEVQRPYAATPSSEASSTSSNPSSATEPDVR
LDSASQPAEKKAE