Protein Info for CSW01_00460 in Vibrio cholerae E7946 ATCC 55056
Annotation: twin-arginine translocase subunit TatA
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to TATA_VIBCH: Sec-independent protein translocase protein TatA (tatA) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
KEGG orthology group: K03116, sec-independent protein translocase protein TatA (inferred from 100% identity to vch:VC0086)MetaCyc: 59% identical to twin arginine protein translocation system - TatA protein (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-181
Predicted SEED Role
"Twin-arginine translocation protein TatA" in subsystem Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related or Twin-arginine translocation system
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (82 amino acids)
>CSW01_00460 twin-arginine translocase subunit TatA (Vibrio cholerae E7946 ATCC 55056) MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGSAVKGFKKAMSEEESNSAANQKDADFE TKNLEQAKTNASAEVKKDKEQA