Protein Info for CSW01_00460 in Vibrio cholerae E7946 ATCC 55056

Annotation: twin-arginine translocase subunit TatA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 82 transmembrane" amino acids 6 to 22 (17 residues), see Phobius details TIGR01411: twin arginine-targeting protein translocase, TatA/E family" amino acids 3 to 48 (46 residues), 76.5 bits, see alignment E=4.3e-26 PF02416: TatA_B_E" amino acids 4 to 55 (52 residues), 54.1 bits, see alignment E=3.7e-19

Best Hits

Swiss-Prot: 100% identical to TATA_VIBCH: Sec-independent protein translocase protein TatA (tatA) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K03116, sec-independent protein translocase protein TatA (inferred from 100% identity to vch:VC0086)

MetaCyc: 59% identical to twin arginine protein translocation system - TatA protein (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-181

Predicted SEED Role

"Twin-arginine translocation protein TatA" in subsystem Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related or Twin-arginine translocation system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (82 amino acids)

>CSW01_00460 twin-arginine translocase subunit TatA (Vibrio cholerae E7946 ATCC 55056)
MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGSAVKGFKKAMSEEESNSAANQKDADFE
TKNLEQAKTNASAEVKKDKEQA