Protein Info for CSW01_00435 in Vibrio cholerae E7946 ATCC 55056

Annotation: EamA/RhaT family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 303 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 33 to 55 (23 residues), see Phobius details amino acids 68 to 88 (21 residues), see Phobius details amino acids 101 to 119 (19 residues), see Phobius details amino acids 127 to 147 (21 residues), see Phobius details amino acids 155 to 173 (19 residues), see Phobius details amino acids 182 to 202 (21 residues), see Phobius details amino acids 214 to 234 (21 residues), see Phobius details amino acids 246 to 265 (20 residues), see Phobius details amino acids 271 to 289 (19 residues), see Phobius details PF00892: EamA" amino acids 6 to 141 (136 residues), 68 bits, see alignment E=5.5e-23 amino acids 155 to 286 (132 residues), 67.2 bits, see alignment E=9.6e-23

Best Hits

KEGG orthology group: None (inferred from 100% identity to vco:VC0395_A2435)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (303 amino acids)

>CSW01_00435 EamA/RhaT family transporter (Vibrio cholerae E7946 ATCC 55056)
MNEKRALSLGLASVLLWSTVATAFKLTLAELNPLQMVTVASIVSALALLVICAAMDKLKL
IVPTLLANPFYYLLLGLINPLAYYLILFKAYSLLPASQAQAINYSWAITLTLMAALFLGQ
RIRKQDWIACAMSYLGVVVIATKGDLLGLQFESPLGVGLALLSTLLWAGYWILNTKNKAD
PIVGVLLGFLLAIPFALALCWHENLNWQGITTQGWLAVTYVGLFEMGITFVLWLSALKNT
QNTARISNLIFASPFISLFLLATIIGEAIHPTTLIGLVLIIAGLVVQQWQGRKAQPSEAK
LNP