Protein Info for CSW01_00160 in Vibrio cholerae E7946 ATCC 55056

Annotation: ATP-dependent protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 507 TIGR00368: Mg chelatase-like protein" amino acids 6 to 493 (488 residues), 708.2 bits, see alignment E=2.7e-217 PF13541: ChlI" amino acids 21 to 142 (122 residues), 159.2 bits, see alignment E=1.4e-50 PF01078: Mg_chelatase" amino acids 190 to 391 (202 residues), 303.9 bits, see alignment E=1.7e-94 PF00158: Sigma54_activat" amino acids 201 to 346 (146 residues), 21.4 bits, see alignment E=6.1e-08 PF07728: AAA_5" amino acids 213 to 353 (141 residues), 41.4 bits, see alignment E=5.1e-14 PF00493: MCM" amino acids 287 to 383 (97 residues), 31.4 bits, see alignment E=3.7e-11 PF13335: Mg_chelatase_C" amino acids 401 to 493 (93 residues), 107.5 bits, see alignment E=1.5e-34

Best Hits

Swiss-Prot: 60% identical to YIFB_ECOLI: Uncharacterized protein YifB (yifB) from Escherichia coli (strain K12)

KEGG orthology group: K07391, magnesium chelatase family protein (inferred from 100% identity to vch:VC0032)

Predicted SEED Role

"MG(2+) CHELATASE FAMILY PROTEIN / ComM-related protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (507 amino acids)

>CSW01_00160 ATP-dependent protease (Vibrio cholerae E7946 ATCC 55056)
MGLAIIHSRASIGVQAPPVTVEVHISNGMPGFTLVGLPETTVKESRDRVRSAIINSRFEF
PAKRITVNLAPADLPKEGGRFDLPIALGILAASDQIARNKLESYEFIGELALSGEIRGVK
GVLPAALAANQVERCLVVPHSNGDQAALVGVERHKSAQSLLEVCADLCGQQTLSLFQSSP
SVQQVSQTRDLQDIIGQQQGKRALEIAAAGNHNLLFLGPPGTGKTMLASRLCDLLPEMSD
EEAMETASIASLTQQEINQHNWKLRPFRAPHHSSSMAALVGGGTIPRPGEISLAHNGLLF
LDEMPEFERKVLDSLREPLESGEIVISRAQGKTRFPARFQLVGALNPSPTGYYEGSQARA
NPQSILRYLSRLSGPLLDRFDMSIEIPALPKGTLANGGDRGESTAAVRQRVWVARERMLA
RSGKVNALLQSREIEQYCPLLKADAEFLESALHRLGLSIRAYHRIIKVARTIADLQGEAQ
IARPHLAEALGYRAMDRLLKQLSAQNV