Protein Info for CCNA_03637 in Caulobacter crescentus NA1000

Annotation: triphosphate tunnel metalloenzyme family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01928: CYTH
  • amino acids 21 to 204 (184 residues), 110.7 bits, E=7.6e-36
• PF05235: CHAD
  • amino acids 237 to 465 (229 residues), 165.5 bits, E=2.1e-52

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_03637)

Predicted SEED Role

"Adenylate cyclase (EC 4.6.1.1)" in subsystem cAMP signaling in bacteria (EC 4.6.1.1)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.6.1.1

Sequence Analysis Tools

See A0A0H3CDM4 at UniProt or InterPro

Protein Sequence (509 amino acids)

>CCNA_03637 triphosphate tunnel metalloenzyme family protein (Caulobacter crescentus NA1000)
MARVPLEQLLTRWGDALFMDHEIELKFLIPPEAAEAILDVLDGEGAVRQLDATYYDTADH
ALRRAGFGLRVRDGEGGRKQTLKSASAGGVFSRGEWEETIAGPTPDRDALARTPVGEMLA
EAALAPVFTARVERTIRMVAAGETLIEVALDRGELSAGERQATVCELELELKTGEPQALF
DLARTLARHAPLRLSLISKAERGYGLAAGDAAPRVRRQTAALGPEASVEAALQAIGQAGL
AHLCAALEALRERPAPDSVHQARVAARRLRAMLKIFKPLSRDAAALALDAELDWLAGELD
AARDLDVFVGEVWEGSAATFEGREAFERGLKAARATAYLRMEAALESPRARDVLLEAAAW
LEAGAWTSDPALAELRTIAAAAYAADRLDRLRRRMKKGAKHFDALDAHARHRLRLKGKTL
RYAAEDLAPLFPNHPRRAERFLAAAKAVQDTLGVLNDRAIRRDLVNSCVHGDATLARAAT
EALLPCDGDKLLRAARGALDDLLDAKSFW