Protein Info for CCNA_03445 in Caulobacter crescentus NA1000

Annotation: M28-family zinc metallopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 805 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 328 to 350 (23 residues), see Phobius details amino acids 362 to 381 (20 residues), see Phobius details amino acids 401 to 420 (20 residues), see Phobius details amino acids 427 to 445 (19 residues), see Phobius details amino acids 451 to 468 (18 residues), see Phobius details amino acids 475 to 494 (20 residues), see Phobius details amino acids 500 to 519 (20 residues), see Phobius details amino acids 526 to 547 (22 residues), see Phobius details amino acids 553 to 575 (23 residues), see Phobius details amino acids 587 to 607 (21 residues), see Phobius details PF04389: Peptidase_M28" amino acids 106 to 294 (189 residues), 159.8 bits, see alignment E=7.2e-51 PF01546: Peptidase_M20" amino acids 133 to 196 (64 residues), 30.3 bits, see alignment E=4e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_03445)

Predicted SEED Role

"FIG00483792: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CEY6 at UniProt or InterPro

Protein Sequence (805 amino acids)

>CCNA_03445 M28-family zinc metallopeptidase (Caulobacter crescentus NA1000)
MKTIRFLGFWICLALGLALGALSQQPPPPVGVTAPATAFSADRAMADVAAIAQKPHPTGS
AEIARVRDHLLSRINALRLEVSVRPGEGFSQHGSDGRTLSAAAVQNLIGILPGRDRSLPA
ILVMSHYDSVHNSPGAADDASGTAAALEIARALKASGPHARDVIFLFTDAEEAGLLGADA
FFARDPSLARVGLVVNMEARGDAGRAAMFQTGPGNGALIGVFGREAKGASGNSMASTVYE
KMPNDTDFTHAVNKGLPGLNLAFIDNQLAYHTPLSRPDHLQRGSLQHMGDQVLPTVRALA
NASELPARTENAIYSDVLGLFMIRYPPAVGWALLALAAALVGFCAWRALAGRGASGWEIA
RGAAGLLLTAASAGLVLHLLGRLLMIDGVQRYYGLLTRFDFLLWGAGLLAAAAGLGVATA
QARGARRIIPCVAALVLGGACSLVGGFDPIGLGLGLAASVLAALALGFRTEVLGAWIGGM
IVVLLLAIAAQVLAPGATVMLTWPLLVAAVGAALVIGIGGTRDKRVALALTTVVGLLAIL
STAQLAAWGGWTFAGVGLMEPAVLAVFAMLAAPALSPLAHDFAATRWAWRAAGIMALVGV
ALTANAARLGGEPSRPAITQALHVADLSTGKAWRVAGLTRLDAWTRAVLPDDGGSEPRQQ
ALAPFWKNPVWMSETRVVPVASPQLTVDRAEDRLLIRLIPAPGAELVSLRLRPSTPLSQP
RLNGRPITLATQAGEWSSLTYHAPDPNGITLSFSTAGPGQVEVAALEHRDGWPTLAKAPP
PKPADLMAFGMSDKTAVLVRGGLSW