Protein Info for CCNA_03140 in Caulobacter crescentus NA1000

Annotation: LysR-family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 296 transmembrane" amino acids 227 to 247 (21 residues), see Phobius details PF00126: HTH_1" amino acids 3 to 62 (60 residues), 78.5 bits, see alignment E=2.9e-26 PF03466: LysR_substrate" amino acids 87 to 290 (204 residues), 130.2 bits, see alignment E=7.4e-42

Best Hits

Swiss-Prot: 100% identical to ILVR_CAUVC: HTH-type transcriptional regulator IlvR (ilvR) from Caulobacter vibrioides (strain ATCC 19089 / CB15)

KEGG orthology group: None (inferred from 100% identity to ccs:CCNA_03140)

Predicted SEED Role

"Transcriptional regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CCG8 at UniProt or InterPro

Protein Sequence (296 amino acids)

>CCNA_03140 LysR-family transcriptional regulator (Caulobacter crescentus NA1000)
MDIRQFRHFAAVAETLHFGRAAERLGITQPPLSQSIQALEKALGAPLFARTKRHVELTAL
GRQWLPHVLEALAAVDALPDTARRLRDGQTGYLSLSFVSTADYSVLPDLVRRYAEAFPGV
EIQLVEATSDVQVPAIQAGERHAGIIIPPPNRSLPAALAYRRLVSEPLVAVTPEAWGAEG
PLDLAALADVPLVLFPRTVAPAFHDLVTGYVAARGQPVRIVQEAIQMQTIISLVSAGLGM
ALAPASLRKLARVGVRYVDLVDPPILETGLVWRRDEAAPTLQGLLRLVTEDGSAPD