Protein Info for CCNA_02743 in Caulobacter crescentus NA1000

Annotation: TonB dependent receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 802 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF07715: Plug" amino acids 65 to 161 (97 residues), 36.9 bits, see alignment E=4.5e-13 PF00593: TonB_dep_Rec" amino acids 315 to 768 (454 residues), 91.1 bits, see alignment E=1.6e-29

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 100% identity to ccs:CCNA_02743)

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C9W4 at UniProt or InterPro

Protein Sequence (802 amino acids)

>CCNA_02743 TonB dependent receptor (Caulobacter crescentus NA1000)
MKARSMSSQRILLSASLLALAAASPALADAQLSDRVDAVVIVARDKAGLLEKQPSQTVFG
IDKPLIETPRSASLVSDLTLERYGVLTLDAATKVAPGTHTASFYGVPGSLNIRGTLAENY
FRGFKRVENRGTYSTPIGGAARIEILRGPPTPVYGAGKVGGLVNFIPKSARDEGRFLAGP
EGEVTATVGSYNKKLLTAQFGAPVSLGGAEGGVYVYGEAEDSHSFYKGIYPRHQTLELSA
DFDLGEGWSTAFGGMLFGSRGDVQTPGWNRLTQDLIDNRTYITGRDTTLKDTDGNGRLTP
NEVGFYPFASALYIPYYGFFSTDAVHTLDAGVGTTKLDRRTVYISPADFSKTDTQTLYFD
LAKDLGEDRALKLQLFHDRQDNKRYVSYGYPSAIDAEVSEVRLTYAFPTTLGAASARTLV
GGSHRWFEGRRRESYNSGMIALDRRDISFGATPTDIIDSPFDDEPGGVGLKWENDNRSTW
KQTGVFVTSDIDIGRLNLILGGRWDRYSVESQDTGFLSYTVTGRKTADRNKATWNASLTY
KLPIGLMPYASYAKAAALEMSQGGDIAPGLVADGSWLSSSDLAEAGVKFQLLRGTLIGSL
AAYRQNRTQITGAIAPPTVQGTRAKGVELEVRWLASERLSFTFAGNNQRTTIKGPDTSFQ
YIPAYTAGVPGAQAYGGSYVVWSFAGLPGRSGDYAYTLTPKSVLSLYGTYTSKGYDWGQA
GATLGVSHVGRTSGTVQNAVRYPAYEVVNASAFVSRGPYTLSVNVDNLFDTFYFTPDADT
YANLGALPGKGREWRATLKRTF