Protein Info for CCNA_02550 in Caulobacter crescentus NA1000

Annotation: DNA polymerase IV-kappa DinB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 418 PF00817: IMS" amino acids 42 to 187 (146 residues), 168 bits, see alignment E=1.3e-53 PF11799: IMS_C" amino acids 273 to 378 (106 residues), 92.4 bits, see alignment E=2.4e-30

Best Hits

Swiss-Prot: 100% identical to DPO4_CAUVC: DNA polymerase IV (dinB) from Caulobacter vibrioides (strain ATCC 19089 / CB15)

KEGG orthology group: K02346, DNA polymerase IV [EC: 2.7.7.7] (inferred from 100% identity to ccs:CCNA_02550)

Predicted SEED Role

"DNA polymerase IV (EC 2.7.7.7)" in subsystem DNA repair, bacterial (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CAY0 at UniProt or InterPro

Protein Sequence (418 amino acids)

>CCNA_02550 DNA polymerase IV-kappa DinB (Caulobacter crescentus NA1000)
MKSLCRDCGWTGATKVARCPACASPRTVFHEELGTLSIAHMDCDAFYASVEKRDDPSLRD
LPVIIGGGKRGVVTTACYIARMSGAKSAMPMFKALKLCPDAVVIKPNFAKYKEESRRIHE
KLDRLTPLIQPLSLDEAWIDLTGTERLHGATPAQMLARLQAEIERDIGLTVSVGLAPNKF
LAKIASELDKPRGFSAIGAAEAQSFLANKPVNILPGVGPATVASLAEIGLRTVGDIAAAD
LKLLANRLGSGGMRLHRLAHGQDSRIVDPDQARKTISAETTFNDDLHKREDLEDELWPLC
EKVAKQARQEGVAGRVATLKLRTPDFKIHTRRRTLAVPTQTARTLFQVARELLSAEPRGL
AYRLIGAGLTEFVDADTAGADMFADEERRALKSETAIDALRGKFGAAAVVTGRALKGR