Protein Info for CCNA_02454 in Caulobacter crescentus NA1000

Annotation: N-methylhydantoinase HyuB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1192 PF05378: Hydant_A_N" amino acids 8 to 180 (173 residues), 181.2 bits, see alignment E=2.3e-57 PF01968: Hydantoinase_A" amino acids 199 to 487 (289 residues), 372.6 bits, see alignment E=2e-115 PF02538: Hydantoinase_B" amino acids 683 to 1191 (509 residues), 672.6 bits, see alignment E=5.1e-206

Best Hits

KEGG orthology group: K01469, 5-oxoprolinase (ATP-hydrolysing) [EC: 3.5.2.9] (inferred from 63% identity to axy:AXYL_03371)

Predicted SEED Role

No annotation

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C9T9 at UniProt or InterPro

Protein Sequence (1192 amino acids)

>CCNA_02454 N-methylhydantoinase HyuB (Caulobacter crescentus NA1000)
MTARGWEFWIDRGGTFTDIVARRPDGSLVTHKLLSENPEHYADAAVAGVRALLPHGAAID
AVKMGTTVATNALLERKGEPTVLAITKGHADALRIGYQARPKLFERNIIKPEALYDRVVE
IDERMSVEGAVLRPLDDAAARAGLQAAYDAGFRAVAIALLHGFRFTDHEARVAMIAREIG
FTQVSVSHEVSPLMKLVGRGDTTVVDAYLSPILRRYVDQVSGALGHDTRLLFMQSNGGLT
DARAFRGKDAILSGPAGGVVGMARTAAEAGFDRVIGFDMGGTSTDVCHYAGAYERAFETV
VAGVRMRAPMMNIHTVAAGGGSICSFDGARLRVGPASAGAVPGPAAYRRGGPLTVTDCNV
MLGKLRPEFFPKVFGPSADQPLDVEAVTRGFEAMAAQITAATGRAMTPQEVAEGFVTIAV
ENMAKAVRQISIQRGYDVTRYVLACFGGAGGQHACLVADALGMSKVMIHPFAGVLSAYGM
GLADLRLIREETVERPLDQADDLAERAERLAAEAQAALRAQDVPMAALETVASLRVKYAG
TDTPLVVPLDEHVRATFEDLHLRRFGFVSPTTPLVVETLSVEAIGHADAGERPSFGASAA
GGAPTPLATVEARMAGEARVTPVFDREALAVGAEVPGPAIIREATGTTVVEPGWRASVDA
QLNLVLERIVALPSRKAIGTDADPVMLEVFNNLFMAVAEEMGFALQNTAYSVNIKERLDF
SCALFDRDGNLIANAPHMPVHLGSMGDSVRAIREARRGDGRGMQPGDVYMLNAPYNGGTH
LPDVTVVMPVFDSEGELRFYVAARGHQGDIGGITPGSMPPSSRTVEEEGVLIENFLLVEG
GRFREAETRALLASGRWPARNPDQNIGDLKAQIAACARGAEALTGMVAEFGLEVVEAYMA
HVQDNAEEAVRRVLATMQSGSLAYELDDGSVVRVAIAVDQAARTARVDFTGTSDQVPTNF
NAPASICRAAALYVFRTLVDDEIPMNDGCLRPVELVIPEGSMLRPRYPAAVVAGNVETSQ
VVVDALYGALGVMAAAQGTMNNFTFGDDRRQYYETICGGSGAGPDFAGTDAVQTHMTNSR
LTDPEVLEARYPVLVEAFSIRRGSGGAGANRGGDGVVRKIGFREPMTATLLSNRRRVAPF
GLEGGEPGALGSARVERAGGQVQALGATDLVEVSAGDVIVIETPGGGGWGKA