Protein Info for CCNA_02118 in Caulobacter crescentus NA1000

Annotation: ATP-dependent helicase, dinG family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 727 transmembrane" amino acids 551 to 567 (17 residues), see Phobius details PF13307: Helicase_C_2" amino acids 552 to 690 (139 residues), 70.8 bits, see alignment E=1.5e-23

Best Hits

KEGG orthology group: K03722, ATP-dependent DNA helicase DinG [EC: 3.6.4.12] (inferred from 100% identity to ccs:CCNA_02118)

Predicted SEED Role

"DinG family ATP-dependent helicase YoaA" in subsystem DNA repair, bacterial DinG and relatives

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.12

Use Curated BLAST to search for 3.6.4.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C881 at UniProt or InterPro

Protein Sequence (727 amino acids)

>CCNA_02118 ATP-dependent helicase, dinG family (Caulobacter crescentus NA1000)
MREAQATFAREATFAFQPREREGEPRMMLAEAGTGVGKTLGYLAPASLWAEANGPSVWVS
TYTRALQRQIERESRSIYPDPKERARKAVVRKGRENYLCLLNFQEQINGAQLGNGDLIGL
ALTVRWARATRDGDMTGGDFPAWLPTLAAVPPSVQASPANLVDRRGECIHAGCQHYRICF
IEKAVRASKRADLVIANHALVLTQAAFDGARTARGLKGDNETTSLKRIVFDEGHHLFEAA
DSAFSAALSGAEAAELRRWIRGPEGRGRRGRGLEARLLDILGDREGARGAMSQAIQAAAA
LPGEGWSGRVAPPDGQINPIGPIENFLVAVIEQLRARSGDRGGADLGLQCDARPATDLVR
ERAPEAAKALAAIEAPLLALARALEDVLDEDAEHLGASERARIEGALRGLDRRARMTLPA
WRSILKAIEDDDVEPSDSDPDFVDWFEATFLYGRVVDAACRRHWVDPTEPLRAAVLSPAH
GVLVTSATLVDPALEDPFALAEMRTGAARLPTAPKVLRLVSPFDYENNAKAFVVTDVNKE
DPRQVSAAMRELFLAAGGGGLGLFTAIRRLKAVHERIAAPLADQGLALYAQHVDPLEVGA
LVDIFRAEEDACLLGTDAIRDGVDVPGRSLRLLVFDRVPWPRPDVLHKARRLRFGGKGYD
DAVARARISQAFGRLIRRADDRGVFVMLDAAAPTRLFSSLPEGVTLERVSLVEAIEATGA
FLAKKEA