Protein Info for CCNA_01852 in Caulobacter crescentus NA1000

Annotation: major facilitator superfamily transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 446 transmembrane" amino acids 47 to 66 (20 residues), see Phobius details amino acids 72 to 96 (25 residues), see Phobius details amino acids 108 to 127 (20 residues), see Phobius details amino acids 132 to 160 (29 residues), see Phobius details amino acids 173 to 195 (23 residues), see Phobius details amino acids 207 to 228 (22 residues), see Phobius details amino acids 259 to 281 (23 residues), see Phobius details amino acids 296 to 318 (23 residues), see Phobius details amino acids 327 to 345 (19 residues), see Phobius details amino acids 354 to 374 (21 residues), see Phobius details amino acids 387 to 409 (23 residues), see Phobius details amino acids 412 to 413 (2 residues), see Phobius details amino acids 415 to 435 (21 residues), see Phobius details PF00083: Sugar_tr" amino acids 37 to 226 (190 residues), 45 bits, see alignment E=7.3e-16 PF07690: MFS_1" amino acids 68 to 403 (336 residues), 51.5 bits, see alignment E=7.7e-18

Best Hits

KEGG orthology group: None (inferred from 100% identity to ccr:CC_1774)

Predicted SEED Role

"MFS permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3CAG5 at UniProt or InterPro

Protein Sequence (446 amino acids)

>CCNA_01852 major facilitator superfamily transporter (Caulobacter crescentus NA1000)
MASELAIPKSSGLERDARRMHADDKGVRPGEIALGVVIGRTSEFFDFFVYAIASVLVFPQ
LVFPFVDRLTGVMLAFGLFALAFIARPFGSVIFGAIDQRYGRGVKLTIALFLLGGSTAVI
SMLPSFAAVGPIAIWALAACRIGQGLALAGAWDGMASLLALNAPENKRGWYAMIPQLGAP
FGFMLASGLFAYFVATLAPADFLDWGWRYPFFAAFAINVVALFARLRIVATEEFGALFEK
RELRPTRVASLLRAEGGNVLIGAFAPLATFAMFHLVTVFPLSWVVLHGDAQQALNFLRIE
LFGALVGVGGILASGWIADRITRQNQLALSALLIGAFSLLAPRLLDGGATGQTAYVVIGF
AILGLSFGQAAGAVSSGFSKRYRYTGAALTSDLSWLIGAGFAPLAALGLASLWGLPAIGL
YLASGALATLLALTIDRTRRRRQAHC