Protein Info for CCNA_01613 in Caulobacter crescentus NA1000

Annotation: rod shape-determining protein MreC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 346 transmembrane" amino acids 15 to 36 (22 residues), see Phobius details PF04085: MreC" amino acids 135 to 274 (140 residues), 103.6 bits, see alignment E=4.2e-34

Best Hits

Swiss-Prot: 100% identical to MREC_CAUVN: Cell shape-determining protein MreC (mreC) from Caulobacter vibrioides (strain NA1000 / CB15N)

KEGG orthology group: K03570, rod shape-determining protein MreC (inferred from 100% identity to ccr:CC_1544)

Predicted SEED Role

"Rod shape-determining protein MreC" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8H610 at UniProt or InterPro

Protein Sequence (346 amino acids)

>CCNA_01613 rod shape-determining protein MreC (Caulobacter crescentus NA1000)
MRFREGPLGDLKVPLTWTAAVALIVAAVIGVAFLLADRRETLQEQAYGVTRQTVDTVARP
VSGAIAAPGRWTGLGLDYVRSYFFTAHENRRLKAELAEMRQWRDRALALQDQNDRFKSLL
GLRTDPPIPMAAARVVSDSRGPFANTRLADAGSERGIVVGNPVLNERGLVGRVVGVSRGV
SRVLLLTDIASRTPVMIDRTNARAILTGDGGPNPKLDYLRGVDPIQQGDRVVTSGDGGVV
PRGLPVGAAVKGLDGRWRVVLFADQASIDYVRILLFKDFAQLADEKQLQARSLPPVTTED
PQTSILSNPVSRPVAPTPSPATATPSAAPAARPATTATPPQTGAPR