Protein Info for CCNA_01071 in Caulobacter crescentus NA1000

Annotation: alpha-ketoglutarate permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 477 transmembrane" amino acids 30 to 48 (19 residues), see Phobius details amino acids 59 to 81 (23 residues), see Phobius details amino acids 89 to 108 (20 residues), see Phobius details amino acids 114 to 137 (24 residues), see Phobius details amino acids 158 to 178 (21 residues), see Phobius details amino acids 190 to 210 (21 residues), see Phobius details amino acids 231 to 253 (23 residues), see Phobius details amino acids 260 to 280 (21 residues), see Phobius details amino acids 287 to 306 (20 residues), see Phobius details amino acids 326 to 344 (19 residues), see Phobius details amino acids 353 to 372 (20 residues), see Phobius details amino acids 378 to 402 (25 residues), see Phobius details amino acids 413 to 435 (23 residues), see Phobius details amino acids 447 to 465 (19 residues), see Phobius details PF00083: Sugar_tr" amino acids 24 to 468 (445 residues), 128.8 bits, see alignment E=2.7e-41 PF07690: MFS_1" amino acids 44 to 301 (258 residues), 44 bits, see alignment E=1.4e-15 amino acids 297 to 460 (164 residues), 49.3 bits, see alignment E=3.7e-17

Best Hits

KEGG orthology group: K03761, MFS transporter, MHS family, alpha-ketoglutarate permease (inferred from 100% identity to ccr:CC_1019)

Predicted SEED Role

"FIG00482706: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C6F0 at UniProt or InterPro

Protein Sequence (477 amino acids)

>CCNA_01071 alpha-ketoglutarate permease (Caulobacter crescentus NA1000)
MTATTEATRLTPVARARAILGGSAGNLVEWYDWFAYAAFTLYFAPAFFPKGDQTVQLLQA
AAVFFLGFVARPIGAWIMGLYADHAGRRAALSVSVSLMCAGAFIIAITPDFQTIGLWAPA
ILLFARVLQGLSVGGEYGASATYMSEMAGKARRGFWSSFHYVTLIAGQLLALGVLIILQR
TLGEEALKEWAWRVPFIIGALLAVVVFWIRRGLEESVSFKRPAQSETLSRGQIISAGAFL
SLTIASGVVGLMGGPLAKAGQYLGAAFLVLFFVSLIVPLIRRHPRESLLIMGLTAGGSLT
FYVYTTYMQKFLVNTAGFSKAQASEISALSLIAFMLMQPLAGWLSDRFGRKPMLIIAFGG
GVLTIWPIMTAISQTNSVGVALALILVGVAFQSCYTAISAVVKAEMFPAEIRALGVALPY
ALANVLFGGTAEMVALAFKHENLESTFYVYVAAVMTIGLICSIILKDTGRHSLIHED