Protein Info for CCNA_00265 in Caulobacter crescentus NA1000

Annotation: AMP nucleosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 484 PF10423: AMNp_N" amino acids 10 to 163 (154 residues), 155.4 bits, see alignment E=9.8e-50 TIGR01717: AMP nucleosidase" amino acids 10 to 484 (475 residues), 706.6 bits, see alignment E=8.4e-217 PF01048: PNP_UDP_1" amino acids 258 to 432 (175 residues), 77.8 bits, see alignment E=8.5e-26

Best Hits

KEGG orthology group: K01241, AMP nucleosidase [EC: 3.2.2.4] (inferred from 100% identity to ccs:CCNA_00265)

Predicted SEED Role

"AMP nucleosidase (EC 3.2.2.4)" in subsystem Purine conversions (EC 3.2.2.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.2.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C461 at UniProt or InterPro

Protein Sequence (484 amino acids)

>CCNA_00265 AMP nucleosidase (Caulobacter crescentus NA1000)
MSNQEKAIAVVERLNDEYERAVGALRDALRAYLEDGTRPDPAARFDGTFAYPELRLTYDP
EALPPKLARSYARVSRPGIYATTVTKPAQFRDYLVEQLTLLLDDFDVEIEIDRSRQEIPY
PYVLDATIDLNQADVRSEDIARFFPTTDLAFIGDEIADGLWNSVLEDNHPLSLFDGLRTD
FSLARLKHYTGAPAEDVQQFILFTNYNRYVDEFVRWGIEQLQQPDSPYTALSCAGGLTIT
ANTVNPELAVAESTWRKHQMPAYHLMAPGGSGVTLVNIGVGPSNAKTICDHLAVLRPQAW
LMIGHCGGLRDTQTIGDYVLAHAYLRDDHVLDAVLPPEIPVPSIAEVQRALYDAAKAISG
DSGDQLKKRLRTGTVVTTDDRNWELRHSLSALRFNQSRAVAIDMESATISAQGYRFRVPY
GTLLCVSDKPLHGEIKLPGQANAFYERAISQHLQIGILACKLLHAEGPNLHSRKLRAFDE
PPFR