Protein Info for CCNA_00211 in Caulobacter crescentus NA1000

Annotation: Porphyromonas-type peptidyl-arginine deiminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF04371: PAD_porph
  • amino acids 5 to 332 (328 residues), 367 bits, E=4.7e-114

Best Hits

KEGG orthology group: K10536, agmatine deiminase [EC: 3.5.3.12] (inferred from 100% identity to ccr:CC_0211)

Predicted SEED Role

"Agmatine deiminase (EC 3.5.3.12)" in subsystem Arginine and Ornithine Degradation or Polyamine Metabolism (EC 3.5.3.12)

MetaCyc Pathways

• L-arginine degradation IV (arginine decarboxylase/agmatine deiminase pathway) (3/3 steps found)
• putrescine biosynthesis II (3/3 steps found)
• superpathway of polyamine biosynthesis II (4/8 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Urea cycle and metabolism of amino groups

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.12

Sequence Analysis Tools

See A0A0H3C5E1 at UniProt or InterPro

Protein Sequence (335 amino acids)

>CCNA_00211 Porphyromonas-type peptidyl-arginine deiminase (Caulobacter crescentus NA1000)
MTVTVPAEWAPHRAMWVGFPSHAELWQEDLEQAQQEVADLARALAGPGAERVRLMVVGDE
AEAAARALLSDTTVEIVRGQFGDIWLRDTGPIFVDDAGKAVAAGFKFNGWGGKYSLEGDD
IVAEQIAAASGAPLVRNDFILEGGALDHDGNGTILTTRQCLLNDNRNPGWDEATANAALT
EALGAKKVLWLGKGLKNDHTDGHVDNLARFVAPGVVACPMGYGLDDPNADIYGDTAKMLA
GMTDSRGSPLQVVRIPSPGKLLDEDGEPIPASHMNFLIANEAVIVPIYAEESGAFAVEVI
KGLFPERQVIGLPSTAILTGGGSFHCISQQEPETA