Protein Info for CA265_RS25225 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: single-stranded-DNA-specific exonuclease RecJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 566 TIGR00644: single-stranded-DNA-specific exonuclease RecJ" amino acids 26 to 561 (536 residues), 538.4 bits, see alignment E=7.6e-166 PF01368: DHH" amino acids 80 to 229 (150 residues), 91.8 bits, see alignment E=6.5e-30 PF02272: DHHA1" amino acids 320 to 441 (122 residues), 74 bits, see alignment E=2.5e-24 PF17768: RecJ_OB" amino acids 456 to 561 (106 residues), 92.8 bits, see alignment E=2.1e-30

Best Hits

KEGG orthology group: K07462, single-stranded-DNA-specific exonuclease [EC: 3.1.-.-] (inferred from 70% identity to phe:Phep_3683)

Predicted SEED Role

"Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-)" in subsystem DNA-replication or DNA Repair Base Excision or DNA repair, bacterial RecFOR pathway (EC 3.1.-.-)

Isozymes

Compare fitness of predicted isozymes for: 3.1.-.-

Use Curated BLAST to search for 3.1.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZBX6 at UniProt or InterPro

Protein Sequence (566 amino acids)

>CA265_RS25225 single-stranded-DNA-specific exonuclease RecJ (Pedobacter sp. GW460-11-11-14-LB5)
MEKRWVLASDCNDAAVTKIAEQLNIDRSLAQILVQRNICDFDQAKDFFRPDLNHLHDPFM
MKDMDVAVARIEAALAAQEKILIYGDYDVDGTTSVALAFSFFSQLTKNIEYYIPDRYLEG
YGISTAGIDYASENGFSLIIALDCGIKSIDKIDYANTLGVDFIICDHHLPGDELPQAIAV
LDPKRSDCEYPFKELAGCGIGFKLAQAYAQKHQLPKETYLQYLDLVMVSIAADIVPVVGE
NRILAYYGLRKLNTNPCEGLRALMEVSGKTENYSITDVVFTLGPRINAAGRIDHAKHAVA
MLLCQVDSNALEQSELINLKNTERKTYDQDITREALALIGESDILINKKTTVVFNENWHK
GVIGIVASRLTEKYYRPTIVLTKSNGHVAGSCRSVVGFDLYEALSGCADLLDQYGGHKFA
AGLTMQQHNVDAFADKFEEIVSASITEELLTPMIRIDAEIELAQIDGKFYRVLSQMGPFG
PENMAPIFVTHNVYLAQHAMAVGANHLKINIKQQNSPIFEGIAFGLAEFENLLQPKVPFS
VCYTLEENVWRDKKRLQLNIKGIKVN