Protein Info for CA265_RS24830 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: beta-N-acetylhexosaminidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 649 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF02838: Glyco_hydro_20b" amino acids 41 to 174 (134 residues), 84.9 bits, see alignment E=1.5e-27 PF00728: Glyco_hydro_20" amino acids 179 to 534 (356 residues), 372.9 bits, see alignment E=3.8e-115 PF13290: CHB_HEX_C_1" amino acids 579 to 628 (50 residues), 23.6 bits, see alignment 8.1e-09 PF13287: Fn3_assoc" amino acids 582 to 633 (52 residues), 28.7 bits, see alignment 2.3e-10

Best Hits

KEGG orthology group: None (inferred from 71% identity to phe:Phep_3656)

Predicted SEED Role

"Beta-hexosaminidase (EC 3.2.1.52)" in subsystem Chitin and N-acetylglucosamine utilization or N-Acetyl-Galactosamine and Galactosamine Utilization (EC 3.2.1.52)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.52

Use Curated BLAST to search for 3.2.1.52

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZBQ4 at UniProt or InterPro

Protein Sequence (649 amino acids)

>CA265_RS24830 beta-N-acetylhexosaminidase (Pedobacter sp. GW460-11-11-14-LB5)
MKKLFLIISCCFFAANTFAQSIVTETEIGDAESAVSPTPIAIIPEPVSLMKKAGTFTLPE
NVTIQTLKSGELKQSIAYLSDRITTATGKFVSTVSNSSHPTIKLILNTQEDAQLGKEGYK
LNVNPTQVVITANQPAGIFYGVQSLLQLFPAEIESKEQVSGIKWKAPCVDVVDYPKLGWR
GLMFDVARHFFTKQEVKQFIDDMVRYKFNLLHLHLVDDEGWRIEIKGLPKLTEIGAWSVK
KTGTFGDFIPPAADEPRTYGGFYTQEDIKELVQYAQERFVNILPEIDVPGHSLAVIASYP
ELSCTPDAVNYKVRSGEKIMDWSRGAPPTALVDNTLCPANEKVYVFLDSVLTQVAKLFPF
GYIHMGGDEAPHNFWEKNDQVKALMQREGLKTIPQVQAYFEKRVEQIVISKGKKFMGWDE
ILEGGVSPTAAVMSWRGMKYGIEAANEKHNVVMSPTDFAYLDYMQADAITEPKVYASLRL
NKAYQFNPVPAGVNAQYVIGAQANLWTEQVFTFRQVEYMVYPRAFAIAESIWSPIEKKNW
TNFVDRTQQHFKRLDFAEIKYSPAIYDPIFTVKRSADKQLMVELTPEIDGLDIYYSFDNS
TPDRFYPKYTAALQVPKDASMLRVITYRGKQPIGRLISIPIADLQKRAR