Protein Info for CA265_RS23920 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: DNA primase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 659 TIGR01391: DNA primase" amino acids 1 to 415 (415 residues), 441.1 bits, see alignment E=2e-136 PF01807: zf-CHC2" amino acids 3 to 96 (94 residues), 119 bits, see alignment E=2.2e-38 PF08275: DNAG_N" amino acids 124 to 253 (130 residues), 133.5 bits, see alignment E=1.7e-42 PF13155: Toprim_2" amino acids 263 to 347 (85 residues), 77.6 bits, see alignment E=2.7e-25 PF13662: Toprim_4" amino acids 263 to 336 (74 residues), 58.2 bits, see alignment E=2.7e-19 PF13362: Toprim_3" amino acids 263 to 353 (91 residues), 30.1 bits, see alignment E=2e-10 PF01751: Toprim" amino acids 263 to 333 (71 residues), 40.4 bits, see alignment E=9.6e-14 PF10410: DnaB_bind" amino acids 381 to 421 (41 residues), 27.4 bits, see alignment 1.1e-09

Best Hits

KEGG orthology group: K02316, DNA primase [EC: 2.7.7.-] (inferred from 73% identity to phe:Phep_0276)

Predicted SEED Role

"DNA primase (EC 2.7.7.-)" in subsystem DNA-replication or Macromolecular synthesis operon (EC 2.7.7.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.-

Use Curated BLAST to search for 2.7.7.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZCD8 at UniProt or InterPro

Protein Sequence (659 amino acids)

>CA265_RS23920 DNA primase (Pedobacter sp. GW460-11-11-14-LB5)
MINRETIDKIMDTARIEEVVGDFVHLKKRGTSLIGNCPFHGEKTPSFHVSVTKGIYKCFG
CGKGGDSVRFIMDHEKYSYPEALKFLANKYNIEVEEAELSPQDAEAQSAKESLYVVSQYA
AAFFVKQLWETDEGRGIGLSYFKERGFREDILKKFEVGYSPDVWDAMTQSATNAGHKLEF
LEATGLSIKNDNGKIYDRFRGRVMFPIHNFTGRIIGFGGRTLKTDKNVPKYVNSPESEIY
HKSNVLYGLFHAKKAIRDLDNCYLAEGYADVLSVHQAGIENVVASSGTSLTVEQIKLIGR
FTQNITILFDGDAAGIKASLRGLDMILEEGLNVKIVSFPDGHDPDSYMHHVGAGAFKTYL
EQNRKDFILYKANVLLKDAGNDPIKRAGIIRDIVESIAKIPDPIKASVFIRECSSLLEID
EHILLSELNKMRSAKLKKSFDNNQRANPSASPKPYSSGPPEPLGPPDDLWDDSAGPMGHE
APVEENEHQEKEIVRLLLAFGHEFVNWDKIDDMYIGSFIMQNLSDVEFDDPLCKRIIDYY
KSEIDNGRLPTSNHFVKHEDRDIADLAITLSTSEYALSENWLNKHLIYVKDESMNLKATI
LGGIFHLKKRKVEKILMNLLKEIKEEKNEDNQMILMQRYGVIKGVEREISKFLGSVIVK