Protein Info for CA265_RS23880 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: preprotein translocase subunit SecA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1158 PF07517: SecA_DEAD" amino acids 6 to 585 (580 residues), 377.5 bits, see alignment E=1.1e-116 PF01043: SecA_PP_bind" amino acids 402 to 541 (140 residues), 103.8 bits, see alignment E=2e-33 PF21090: P-loop_SecA" amino acids 688 to 758 (71 residues), 114.6 bits, see alignment 1.2e-36 amino acids 759 to 827 (69 residues), 112.5 bits, see alignment 5.5e-36 PF07516: SecA_SW" amino acids 829 to 1078 (250 residues), 204.1 bits, see alignment E=6.1e-64 PF02810: SEC-C" amino acids 1138 to 1155 (18 residues), 39.1 bits, see alignment (E = 1.4e-13)

Best Hits

Predicted SEED Role

"Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZC37 at UniProt or InterPro

Protein Sequence (1158 amino acids)

>CA265_RS23880 preprotein translocase subunit SecA (Pedobacter sp. GW460-11-11-14-LB5)
MLGFLAKVFGSKSERDIKAIQPLVVKINEHYSKLSALSNDELRGKTTEFKDKISAFLTDI
DEKISALKAEAESEDLDLHQKTAIYDQVDALGKDRDTELEKVLLEILPEAFAVVKETSRR
LSENDYLEVTATQFDRDYAARKNNVKIVGDKAQWANKWDAAGTEVAWNMVHYDVQLIGGI
VLHSGKIAEMATGEGKTLVSTLPAYLNALAGQGVHIVTVNDYLARRDSEWNGPLFEFHGL
TVDCIDKHEPNSEERRKAYAADITYGTNNEFGFDYLRDNMSQTPDQLVQRKQHFAMVDEV
DSVLIDDARTPLIISGPIPRGDEHEFYELKPRIERLVNAQKAYVTQALNEAKKLINAGNS
GTEEGEGGLALLRAYRGLPKNKALIKFLSESGVRGLLLKTENHYMADQSKNMPKVDSELY
FYIDEKNNQVELTEKGIELITQSGEDPHFFVLPDVGTEVADLEKSDLPLEEKVVQKDALM
RDYSVKAERIHSVNQLLKAYTLFEIDVEYIIDEGKIKIVDEQTGRIMDGRRYSDGLHQAI
EAKENVKVEDATQTYATVTLQNYFRMYHKLCGMTGTATTEAGEFWSIYKLDVVEIPTNRN
ISRKDEQDYVYRTVREKYNAVASEIQFLVFPYSHYETEYELDKEGNPKLKDGKPVIKYDP
TGRAVPKLDAKGALIPAVNPQTGQLEPQAGRPVLVGTTSVEISELLSRMLKLRGIKHNVL
NAKMHQKEADIVAEAGQAGTVTIATNMAGRGTDIKLGAGVKEAGGLAIVGTERHESRRVD
RQLRGRAGRQGDPGSSQFFVSLEDNLMRLFGSERISGIMVRMGIEDGEVIQHSMITKSIE
RAQKKVEENNFGIRKRLLEYDDVMNSQRTVIYAKRKNALFGERLDVDMNNMVFDVAEDIV
SEYKQEGNFDGFKLEVIKNFSLDTAITEKEFTSTSIPQLTERLFEEAEAFYARKSEAIIQ
QSLPVLTQVYQERGEHIEQIVVPFTDGIRGIQVAVDLKKAIDNKGKEVVRSFEKTIVLAL
IDDSWKEHLREMDDLKQSVQNAVYEQKDPLVIYKMEAFNLFKNMLNAVNKEVVSFLYKGG
IPVQQEPDQVREAPAPVKQPKLQTTKQEFGREEPGIEFGDTREAVPQQPIRKEATVGRNE
PCPCGSGKKYKNCHGANL