Protein Info for CA265_RS22975 in Pedobacter sp. GW460-11-11-14-LB5
Updated annotation (from data): 3-keto-alpha-glucoside 1,2-lyase
Rationale: Specifically important in carbon source D-Trehalose dihydrate. Also important for utilization of maltitol, so it's probably active on other substrates as well. Distantly related to 3-keto-alpha-glycoside lyase BT2157 (see PMID:38898276, PMID:37932298). This protein has a signal peptide so is probably periplasmic.
Original annotation: hypothetical protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 64% identity to cpi:Cpin_5826)Predicted SEED Role
"putative multi-domain protein"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A1X9ZBL6 at UniProt or InterPro
Protein Sequence (260 amino acids)
>CA265_RS22975 3-keto-alpha-glucoside 1,2-lyase (Pedobacter sp. GW460-11-11-14-LB5) MNKYTLLFIPALFAGQAMAQDKKPDPAKDPKTTEVWEPVPKVVTPGKLPQDAPSDATILF GGRNLDAWHSVKDPSKPAEWTIDDGFFTVKKGTGNIETNKKFTDYQLHMEWKIPENISGE GQARGNSGVFLASTGGGDNGYEIQIMDAYNNKTYVNGQTGSVYKQAIPLANANKKPGEWQ YYDIIWNAPRFNEDGTVQKPASVTVFLNGVLLQNGFVLKGETRYIGAPEYKKHGPSSIKL QDHGDPSPAISYRNIWVREL