Protein Info for CA265_RS22965 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: leucyl/phenylalanyl-tRNA--protein transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 210 TIGR00667: leucyl/phenylalanyl-tRNA--protein transferase" amino acids 30 to 207 (178 residues), 209.8 bits, see alignment E=1.3e-66 PF03588: Leu_Phe_trans" amino acids 33 to 198 (166 residues), 245.8 bits, see alignment E=8.9e-78

Best Hits

Swiss-Prot: 60% identical to LFTR_FLAJ1: Leucyl/phenylalanyl-tRNA--protein transferase (aat) from Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101)

KEGG orthology group: K00684, leucyl/phenylalanyl-tRNA--protein transferase [EC: 2.3.2.6] (inferred from 63% identity to phe:Phep_4162)

MetaCyc: 50% identical to leucyl/phenylalanyl-tRNA--protein transferase (Escherichia coli K-12 substr. MG1655)
Leucyltransferase. [EC: 2.3.2.6]; 2.3.2.6 [EC: 2.3.2.6]; 2.3.2.6 [EC: 2.3.2.6]; 2.3.2.6 [EC: 2.3.2.6]

Predicted SEED Role

"Leucyl/phenylalanyl-tRNA--protein transferase (EC 2.3.2.6)" in subsystem Protein degradation (EC 2.3.2.6)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZBV3 at UniProt or InterPro

Protein Sequence (210 amino acids)

>CA265_RS22965 leucyl/phenylalanyl-tRNA--protein transferase (Pedobacter sp. GW460-11-11-14-LB5)
MFFQLPDDHPGFPDPALAEEDGLLAIGGDLSTERLLMAYSNGIFPWFSEGEPILWYSPHE
RCVIYPDQIRISKSMRKILKQEIFKITFNQAFAEVIRNCATTERKGQDGTWITNEMQAAY
INLHQQGYAHSVEVWQADQLVGGLYGLKVNRVFCGESMFSHVSNASKAALIFLSKMNIDL
IDCQLPNDHLMSLGAEMMDRETFMGILRKD