Protein Info for CA265_RS22795 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: antibiotic ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 605 transmembrane" amino acids 20 to 43 (24 residues), see Phobius details amino acids 84 to 105 (22 residues), see Phobius details amino acids 174 to 203 (30 residues), see Phobius details amino acids 271 to 295 (25 residues), see Phobius details PF00664: ABC_membrane" amino acids 54 to 321 (268 residues), 130.3 bits, see alignment E=1.7e-41 PF00005: ABC_tran" amino acids 382 to 531 (150 residues), 114.3 bits, see alignment E=1e-36

Best Hits

Swiss-Prot: 37% identical to MSBA_SYNAS: Lipid A export ATP-binding/permease protein MsbA (msbA) from Syntrophus aciditrophicus (strain SB)

KEGG orthology group: K11085, ATP-binding cassette, subfamily B, bacterial MsbA [EC: 3.6.3.-] (inferred from 64% identity to shg:Sph21_1607)

Predicted SEED Role

"Lipid A export ATP-binding/permease protein MsbA" in subsystem ZZ gjo need homes

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZBI3 at UniProt or InterPro

Protein Sequence (605 amino acids)

>CA265_RS22795 antibiotic ABC transporter ATP-binding protein (Pedobacter sp. GW460-11-11-14-LB5)
MKTYFRLLSFAKPIEKFAIPYIIATLFAIIFNTFLFTLLGPLLETLFIKDAPTTLSKVSS
SIDFMGKFSQYIQHAIDAYGKTETLKLVCIVIVVTVILANLFRYLSQRFMEDLRVHTLLN
LRRTVFNNVMNLHVGFFNNERKGDIISKVASDVQVVQFTVTNTLQVIFKEPLQLLFYVGV
LISISVKLTLFSLLVIPVSGFIISKIVKRLKHQAKESHESFAKMIGFLDESLSGIKIIKA
FNATPRIKDKFDQENKFYSYLNRKMARRQQLASPVSQTLGVFVVVFIVLYGGTMILTGQG
DLTPAKFLVYIATFSQVMQPVKALTDSFSGIHSGIAAGERVLDLMDTKPLLVNAPDAKVL
DGFNSAISLQDVSFSYGEKQILNSITFEIEKGKTVALVGPSGGGKSTLMDLLPRFHDPKS
GVIKIDGHDYKELTVESIRAQMGTVNQESFLFNDTIFNNIAFAKPDASMEEVVAAAKIAN
AHDFIENAENGYQSLVGDRGNKLSGGQKQRVCIARAVLANPPIMLLDEATSALDTESEKL
VQDALNNLMKNRTSIVIAHRLSTIQHADKIVVIDKGSVVETGSHSELMAKNGLYKRLIDM
QAFTE