Protein Info for CA265_RS22390 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: alpha-ketoglutarate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 428 transmembrane" amino acids 57 to 76 (20 residues), see Phobius details amino acids 88 to 106 (19 residues), see Phobius details amino acids 112 to 133 (22 residues), see Phobius details amino acids 155 to 176 (22 residues), see Phobius details amino acids 188 to 207 (20 residues), see Phobius details amino acids 239 to 257 (19 residues), see Phobius details amino acids 277 to 296 (20 residues), see Phobius details amino acids 305 to 325 (21 residues), see Phobius details amino acids 332 to 354 (23 residues), see Phobius details amino acids 366 to 387 (22 residues), see Phobius details amino acids 399 to 416 (18 residues), see Phobius details PF00083: Sugar_tr" amino acids 20 to 222 (203 residues), 108.9 bits, see alignment E=3.2e-35 amino acids 235 to 424 (190 residues), 42.1 bits, see alignment E=5.5e-15 PF07690: MFS_1" amino acids 47 to 370 (324 residues), 99.3 bits, see alignment E=2.3e-32 amino acids 250 to 390 (141 residues), 38.1 bits, see alignment E=9.3e-14

Best Hits

Swiss-Prot: 54% identical to KGTP_ECOLI: Alpha-ketoglutarate permease (kgtP) from Escherichia coli (strain K12)

KEGG orthology group: K03761, MFS transporter, MHS family, alpha-ketoglutarate permease (inferred from 70% identity to phe:Phep_3393)

MetaCyc: 54% identical to alpha-ketoglutarate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-23

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZCZ7 at UniProt or InterPro

Protein Sequence (428 amino acids)

>CA265_RS22390 alpha-ketoglutarate transporter (Pedobacter sp. GW460-11-11-14-LB5)
MHQNEIKDVEYRLKSIFGGSVGNLVEWYDWYTYSAFALYFSPAFFPNSNPTAQLLDTAGI
FAVGFLMRPIGGWLFGSIADKLGRKRSMTLSVLIMAIGSLIIGLTPGYKQIGIAAPLLLI
FARLIQGLSTGGEYGTSATYLSEMATKKHRGFYSSFQYVTLIGGQLLALGIQLILQNWLL
TPAELHEWGWRIPFFIGAILSFIALYLRRHIDETSAFKSKNTADKKGGIAVLMKYPKEVF
TVVGLTLGGTIAFYTFSTYMQKFLVNTVHLSKETSTTLSFISLLVFVVLQPLFGLLSDKI
GRKPLLIGFGVLGTLCTYPILTGLAGESNTTIIFLLMIGALIIVSGYTSINAVVKAELFP
AEIRALGVGLPYALTVAIFGGTAEYFALWFKNIGHENYFYWYVTGCILISLILYTTMKDT
KHHSKIED