Protein Info for CA265_RS22330 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: peptidase C39

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 703 transmembrane" amino acids 160 to 182 (23 residues), see Phobius details amino acids 197 to 216 (20 residues), see Phobius details amino acids 271 to 292 (22 residues), see Phobius details amino acids 298 to 318 (21 residues), see Phobius details amino acids 391 to 412 (22 residues), see Phobius details amino acids 418 to 437 (20 residues), see Phobius details PF03412: Peptidase_C39" amino acids 5 to 134 (130 residues), 119.4 bits, see alignment E=3e-38 TIGR01193: ABC-type bacteriocin transporter" amino acids 7 to 698 (692 residues), 529.9 bits, see alignment E=5.7e-163 PF00664: ABC_membrane" amino acids 164 to 431 (268 residues), 171.9 bits, see alignment E=7.4e-54 PF00005: ABC_tran" amino acids 493 to 641 (149 residues), 104.8 bits, see alignment E=1.8e-33

Best Hits

KEGG orthology group: K06147, ATP-binding cassette, subfamily B, bacterial (inferred from 80% identity to phe:Phep_3347)

Predicted SEED Role

"Lipid A export ATP-binding/permease protein MsbA" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZAE7 at UniProt or InterPro

Protein Sequence (703 amino acids)

>CA265_RS22330 peptidase C39 (Pedobacter sp. GW460-11-11-14-LB5)
MSTKVKQRDITDCGAACLASIAAHYKLDLAVARIRQLAGTDKKGTTVLGLVEAAQKLGFE
AKGVKAPFDSLFKIPTPAIAHIIVNDILQHYVVIYKVNSKFIEVMDPIDGKVHRKTHDEF
KKEWTGALVLLLPSEDFQIGNEKKSIQGRFWSLIKPHKGILTQVLFGAIVYTVLGLSTSI
FVQKLVDFVLVDGNHNLLNLMSIAMMVILMVQLFIGSAKTIFTLKTGQLIDSQLILGYYK
HLLRLPQQFFDTMRVGEIISRINDAVKIRAFLNDVCVNFVVNIFIVFFSFIMMFTYYWKL
ALITLTVIPLYLVIYFITDKFNKRTQRRLMEDAAELESQLVESLNAVGTIKRFGLEDHAN
DKTETRFIKLLQAGFKSNINAVVSGTSTEFISRMITIVLLWVGAGYVLSNSITPGELLSF
YTLIGYFTGPVSSLIGMNKTVQDAVIAADRLFEIMDLERESDENQIELSAAKIGDIHFEN
VSFRYGARLPVFENLNLTIPQGKFTAIVGESGSGKSTLMSILQNIYPIQAGNVRIGKYDL
KYITNSSLRRMVSVVPQQIDLFAGNVIDNIAIGEEEPDMQRIIDIATKLGLIGFIEALPK
GFQTYLGENGTSLSGGQRQRIAIARALYRDPEILILDEATSSLDSVSEQHVQRMIEFLKA
EQKTVIVITHRSSTLNNADKIIVLDKGVVVEQGSHQELKYHLA